Cannabidiol (CBD) acts very differently from tetrahydrocannabinol (THC); it's non-psychoactive and not intoxicating, and it does not induce abuse or dependence. It's highly fat-soluble; thus, it enters the brain easily. However, it has low solubility and absorption in water, which produces variable pharmacokinetics and contributes to the difficulty in studying its multiple mechanisms of action. Bioavailability via inhalation averages about 31 percent, while oral bioavailability is only about 6 percent in humans. Therefore, don't bother eating it.
1) anxiety is prevalent among the clinical population - half of the OAB subjects had anxiety symptoms, and one quarter of OAB subjects had moderate to severe anxiety symptoms; 2) OAB subjects reported higher anxiety symptoms compared to controls; 3) OAB patients with anxiety reported more severe OAB/incontinence symptoms, worse quality of life, and more psychosocial difficulties compared to OAB patients without anxiety.
In Mahayana Buddhism, sunyata - often translated as "emptiness" - doesn't mean that nothing matters. It means nothing exists with a permanent essence. Everything is constantly changing and without fixed self-nature. Seeing through the illusion of an enduring, separate self can be liberating.
As we age and experience the death of parents and peers, we become increasingly aware of our mortality. Such awareness may trigger anxiety and prompt preparations, such as writing wills and advance directives.
Not someone, but myself, unfortunately. The last flight I was on was my first time leaving town without my kids. The anxiety I got from leaving them and being a day's worth of traveling away made me feel physically sick. I knew we'd miss them and I knew it would be hard, but I'd generally been strong about it and despite that aspect, very excited. Once we got as far as boarding the plane, I was nauseous from anxiety.