Clonal driver neoantigen loss under EGFR TKI and immune selection pressures - NatureEGFR mutations in lung adenocarcinoma improve outcomes with TKIs, but resistance often develops, prompting exploration of new immune-based therapies.
RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - NatureVaccine-induced T cells correlate with significantly improved recurrence-free survival in PDAC patients at extended follow-up.
Fate induction in CD8 CAR T cells through asymmetric cell division - NatureAsymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - NatureVaccine-induced T cells correlate with significantly improved recurrence-free survival in PDAC patients at extended follow-up.
Fate induction in CD8 CAR T cells through asymmetric cell division - NatureAsymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
Woman in cancer remission for record 19 years after CAR-T immune treatmentCAR T-cell therapy has shown groundbreaking success, particularly for a girl with nerve-cell cancer who is now cancer-free after 19 years.
Woman who had pioneering cancer treatment 18 years ago still in remissionA woman has remained cancer-free for over 18 years following CAR T-cell therapy for neuroblastoma, showing promise for solid tumor treatments.
Do cutting-edge CAR-T-cell therapies cause cancer? What the data sayCAR-T-cell therapy faces FDA investigation for potential link to lymphomas.
Revolutionary CAR-T cell therapy looks to break through beyond blood cancerCAR-T cell therapy revolutionizes blood cancer treatment by enhancing T-lymphocytes to combat tumors, with potential for wider application beyond hematological cancers.
Woman in cancer remission for record 19 years after CAR-T immune treatmentCAR T-cell therapy has shown groundbreaking success, particularly for a girl with nerve-cell cancer who is now cancer-free after 19 years.
Woman who had pioneering cancer treatment 18 years ago still in remissionA woman has remained cancer-free for over 18 years following CAR T-cell therapy for neuroblastoma, showing promise for solid tumor treatments.
Do cutting-edge CAR-T-cell therapies cause cancer? What the data sayCAR-T-cell therapy faces FDA investigation for potential link to lymphomas.
Revolutionary CAR-T cell therapy looks to break through beyond blood cancerCAR-T cell therapy revolutionizes blood cancer treatment by enhancing T-lymphocytes to combat tumors, with potential for wider application beyond hematological cancers.
Drug that melts away' tumours could replace surgery for bowel cancer, say doctorsPembrolizumab immunotherapy before surgery boosts bowel cancer cure rates, potentially replacing chemotherapy and surgery.
Tak Mak, immunologist: The immune system is the orchestra for most of life's symphonies'Immunotherapy represents a revolutionary advancement in cancer treatment, surpassing traditional methods like chemotherapy and radiotherapy in efficacy.
A golden age of cancer treatment? podcastCancer treatment has evolved from limited options to advanced personalized therapies.Investment in new technologies has transformed cancer care significantly.Challenges remain in equitable distribution of effective cancer treatments.
How to trick the immune system into attacking tumoursScientists can trick the immune system into attacking disguised tumours to potentially treat cancer.The new technique requires more clinical testing to verify its true efficacy.
B-Cells Hold Promise for Treating Glioblastoma - News CenterB-cell therapy may offer a new, promising approach to treating glioblastoma.
Pembrolizumab improves outcomes in high-risk bladder cancerPembrolizumab nearly doubles cancer-free duration post-invasive bladder surgery, offering a crucial treatment option for high-risk patients.
Drug that melts away' tumours could replace surgery for bowel cancer, say doctorsPembrolizumab immunotherapy before surgery boosts bowel cancer cure rates, potentially replacing chemotherapy and surgery.
Tak Mak, immunologist: The immune system is the orchestra for most of life's symphonies'Immunotherapy represents a revolutionary advancement in cancer treatment, surpassing traditional methods like chemotherapy and radiotherapy in efficacy.
A golden age of cancer treatment? podcastCancer treatment has evolved from limited options to advanced personalized therapies.Investment in new technologies has transformed cancer care significantly.Challenges remain in equitable distribution of effective cancer treatments.
How to trick the immune system into attacking tumoursScientists can trick the immune system into attacking disguised tumours to potentially treat cancer.The new technique requires more clinical testing to verify its true efficacy.
B-Cells Hold Promise for Treating Glioblastoma - News CenterB-cell therapy may offer a new, promising approach to treating glioblastoma.
Pembrolizumab improves outcomes in high-risk bladder cancerPembrolizumab nearly doubles cancer-free duration post-invasive bladder surgery, offering a crucial treatment option for high-risk patients.
Bone marrow niches orchestrate stem-cell hierarchy and immune toleranceHierarchical arrangements of haematopoietic stem cells in niches influence their regenerative potential and immune privilege.
The Cure's Roger O'Donnell reveals rare and aggressive' blood cancer diagnosisEarly detection and testing for lymphoma can lead to better outcomes.Emotional support is crucial for those suffering from illness.
Intelligencer's 20 Most-Read Stories in 2024In-depth reporting on political dynamics and medical advancements engaged readers in 2024.
The Cure's Roger O'Donnell reveals rare and aggressive' blood cancer diagnosisEarly detection and testing for lymphoma can lead to better outcomes.Emotional support is crucial for those suffering from illness.
Intelligencer's 20 Most-Read Stories in 2024In-depth reporting on political dynamics and medical advancements engaged readers in 2024.
HERVolution Therapeutics Raises $11.7M Series A to Advance Dark Genome-Based Immunotherapies for Cancer and AgingHERVolution secures $11.7 million Series A funding to advance HERV-targeting immunotherapies.
Dutch biotech firm Citryll secures 85M funding - Silicon CanalsCitryll has raised €85M in Series B funding for its innovative therapy targeting Neutrophil Extracellular Traps (NETs) in inflammatory diseases.
HERVolution Therapeutics Raises $11.7M Series A to Advance Dark Genome-Based Immunotherapies for Cancer and AgingHERVolution secures $11.7 million Series A funding to advance HERV-targeting immunotherapies.
Dutch biotech firm Citryll secures 85M funding - Silicon CanalsCitryll has raised €85M in Series B funding for its innovative therapy targeting Neutrophil Extracellular Traps (NETs) in inflammatory diseases.
Immunotherapy achieves remarkable survival rates in a handful of tumorsImmunotherapy has significantly improved prognosis and survival rates for patients with metastatic melanoma over the past 15 years.
Researchers discover possible key to enhance immunotherapy cancer treatment: certain anti-inflammatory drugsThe discovery of PD-1 has revolutionized cancer treatment through immunotherapy, but resistance remains a challenge.
YouTube shares a final blog post from Susan Wojcicki on fighting lung cancerThe author's diagnosis led to a significant life change, focusing on health and cancer research.
Drug Reprograms Immune Responses to Target Glioblastoma - News CenterUsing a novel drug to target the STING pathway in glioblastoma reprograms immune responses, offering a promising therapeutic strategy for non-responsive patients.
EU backs Dutch scaleup Lumicks to fast-track discovery of cancer treatmentsLumicks has secured €20mn funding to enhance immunotherapy drug discovery by improving its real-time cell avidity analyser technology.
Understanding How Deadly Lung Cancers Control the Local Immune System - News CenterDiscovery of HDAC3's role in regulating immune response to KRAS-driven lung cancer indicates potential for new therapeutic approaches.
Immunotherapy achieves remarkable survival rates in a handful of tumorsImmunotherapy has significantly improved prognosis and survival rates for patients with metastatic melanoma over the past 15 years.
Researchers discover possible key to enhance immunotherapy cancer treatment: certain anti-inflammatory drugsThe discovery of PD-1 has revolutionized cancer treatment through immunotherapy, but resistance remains a challenge.
YouTube shares a final blog post from Susan Wojcicki on fighting lung cancerThe author's diagnosis led to a significant life change, focusing on health and cancer research.
Drug Reprograms Immune Responses to Target Glioblastoma - News CenterUsing a novel drug to target the STING pathway in glioblastoma reprograms immune responses, offering a promising therapeutic strategy for non-responsive patients.
EU backs Dutch scaleup Lumicks to fast-track discovery of cancer treatmentsLumicks has secured €20mn funding to enhance immunotherapy drug discovery by improving its real-time cell avidity analyser technology.
Understanding How Deadly Lung Cancers Control the Local Immune System - News CenterDiscovery of HDAC3's role in regulating immune response to KRAS-driven lung cancer indicates potential for new therapeutic approaches.
Immunotherapy Shows Potential to Treat Deadly Thyroid Cancer - News CenterCombination immunotherapy shows promise in treating anaplastic thyroid carcinoma, a rare and aggressive form of thyroid cancer, with a response rate of 30%.
What are cancer vaccines and have scientists finally found a cure?Cancer vaccines are personalized treatments designed to help the patient's immune system recognize and eliminate cancer cells.
World-first lung cancer vaccine trials launched across seven countriesThe world's first mRNA lung cancer vaccine, BNT116, shows promise in treating non-small cell lung cancer and improving survival rates.
Immunotherapy Shows Potential to Treat Deadly Thyroid Cancer - News CenterCombination immunotherapy shows promise in treating anaplastic thyroid carcinoma, a rare and aggressive form of thyroid cancer, with a response rate of 30%.
What are cancer vaccines and have scientists finally found a cure?Cancer vaccines are personalized treatments designed to help the patient's immune system recognize and eliminate cancer cells.
World-first lung cancer vaccine trials launched across seven countriesThe world's first mRNA lung cancer vaccine, BNT116, shows promise in treating non-small cell lung cancer and improving survival rates.
Current and former smokers can now get lungs checked at mobile unit, as pilot study aims to improve the early detection of cancerThe pilot program aims to enhance early detection and treatment of lung cancer in Ireland through innovative screening methods.
Natural killer cells show their cancer-fighting worthNatural killer (NK) cells from umbilical-cord blood show promise as a potentially effective and less side-effect-prone alternative to T-cell therapies for blood cancer treatment.
Combination Treatment Extends Survival in Advanced Bladder Cancer - News CenterImmunotherapy combined with chemotherapy and surgery significantly improves survival in muscle-invasive bladder cancer patients compared to chemotherapy alone.
Treating Skin Cancer Without Risking Transplanted Kidneys in Organ Recipients - News CenterImmunosuppressants and immunotherapy alone may not prevent organ rejection in kidney transplant recipients with skin cancer.Transplant recipients face higher risk for skin cancer and limited treatment options due to potential rejection from traditional therapies.
Skin Patch Improves Treatment for Pediatric Milk Allergies - News CenterDaily immunotherapy via dermal patch reduced risks in children with cow's milk allergy.
Natural killer cells show their cancer-fighting worthNatural killer (NK) cells from umbilical-cord blood show promise as a potentially effective and less side-effect-prone alternative to T-cell therapies for blood cancer treatment.
Combination Treatment Extends Survival in Advanced Bladder Cancer - News CenterImmunotherapy combined with chemotherapy and surgery significantly improves survival in muscle-invasive bladder cancer patients compared to chemotherapy alone.
Treating Skin Cancer Without Risking Transplanted Kidneys in Organ Recipients - News CenterImmunosuppressants and immunotherapy alone may not prevent organ rejection in kidney transplant recipients with skin cancer.Transplant recipients face higher risk for skin cancer and limited treatment options due to potential rejection from traditional therapies.
Skin Patch Improves Treatment for Pediatric Milk Allergies - News CenterDaily immunotherapy via dermal patch reduced risks in children with cow's milk allergy.
Revolutionary Approaches to Egg Allergy TreatmentInnovative treatments for egg allergies are emerging, transforming management strategies and offering hope for affected individuals and families.
Combination Therapy May Improve Outcomes for Advanced Bladder Cancer - News CenterCombination therapy of pembrolizumab chemotherapy and oncolytic adenovirus shows promise for immunotherapy-resistant non-muscle-invasive bladder cancer.
Investigators Discover New Therapeutic Target for Pediatric Brain Cancers - News CenterTargeting TIM3 protein may enhance survival in pediatric brain cancer treatments, specifically low-grade astrocytoma, presenting a potential new therapeutic option.
Combination Therapy May Improve Outcomes for Advanced Bladder Cancer - News CenterCombination therapy of pembrolizumab chemotherapy and oncolytic adenovirus shows promise for immunotherapy-resistant non-muscle-invasive bladder cancer.
Investigators Discover New Therapeutic Target for Pediatric Brain Cancers - News CenterTargeting TIM3 protein may enhance survival in pediatric brain cancer treatments, specifically low-grade astrocytoma, presenting a potential new therapeutic option.
AI assistance for planning cancer treatmentAI algorithms are aiding oncologists in predicting responders to immunotherapy, improving treatment outcomes.
How mRNA vaccines could be personalized cancer curesPersonalized cancer vaccines take time to produce, allowing cancer to spread.
Targeting Protein Interactions May Boost Antitumor Immunity in Breast Cancer - News CenterTargeting OTUD4-CD73 axis boosts immune response in immune-suppressive breast cancers.
FDA approves bladder cancer treatment by Culver City companyFDA approved new bladder cancer treatment Anktiva by ImmunityBio, activating immune response in patients who didn't respond to prior therapies.
Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells - NatureTiragolumab combined with atezolizumab shows improved outcomes in cancer treatmentHigh baseline of intratumoral macrophages and regulatory T cells may lead to better outcomes in patients receiving combination therapy.
New era of medicine breaks through against the most aggressive lung cancerNew drugs offer hope for small cell lung cancer treatment.
New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells - News CenterUltrasound technology penetrated the blood-brain barrier to administer immunotherapy and chemotherapy for glioblastoma, boosting immune recognition of cancer cells.
Protein May Hold Key to Transplant Tolerance - News CenterProtein HIF-2a contributes to heart transplant tolerance in mice, offering potential for precise immunotherapy for humans.