Breakthrough lung cancer treatment supercharges immune cells with mitochondria
Briefly

Researchers have developed a mitochondrial therapy for enhancing lung cancer treatment by transplanting healthy mitochondria into tumors, which increases immune response and chemotherapy efficacy. This method, when combined with the drug cisplatin, improves immune cell infiltration and reverses harmful tumor metabolism, allowing for better treatment outcomes. Despite chemotherapy being the primary treatment for advanced non-small cell lung cancer (NSCLC), challenges like toxic side effects and tumor resistance limit its effectiveness. The new approach aims to overcome these challenges by making tumors more sensitive to chemotherapy while restoring immune function.
A new mitochondrial therapy turbocharges lung cancer treatment by restoring immune power and making tumors more vulnerable to chemotherapy, reversing their resistance and toxic metabolism.
Combining mitochondrial transplantation with cisplatin not only enhanced immune cell infiltration but also reversed tumor metabolism and improved the drug's effectiveness.
This innovative approach transforms mitochondria from mere energy suppliers into active allies in cancer therapy, showing potential to reshape how we treat aggressive lung tumors.
Chemotherapy remains a cornerstone of lung cancer treatment, but its effectiveness is hampered by toxic side effects and emerging resistance.
Read at ScienceDaily
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