#clinical-trials

#clinical-trials

The AMP SCZ initiative is leveraging a large investment from NIMH and public-private partners to conduct the most comprehensive, longitudinal study in individuals at risk for schizophrenia.

Prof Sir John Burn from Newcastle University stated that a study involving 1,879 individuals with Lynch syndrome shows a low dose of 75mg aspirin effectively reduces cancer risk as larger doses.

"ExciteOSA is a medical device designed to improve sleep for individuals with sleep apnoea, tackling issues that lead to severe health problems."

The BayesPPDSurv R package allows for Bayesian analysis of time-to-event outcomes by integrating historical data to inform treatment effects, enhancing clinical trial efficiency.

The study found that, in people with prediabetes, metformin lowered the risk of diabetes by roughly a third; the life-style intervention cut the risk by more than half.

As of 2025, the NIH has awarded about $2.8 billion less than usual at this point over the past five years, indicating a restoration of funding flow.

A study highlighted how placebo surgeries often yield better outcomes than actual surgeries, raising significant ethical concerns about deception in medical treatment.

"I think it helped," says her husband, Ken Bell. "But I'm not sure." That sort of uncertainty is common when it comes to Leqembi and Kisunla, two new Alzheimer's drugs approved since 2023.