#clinical-trials
#clinical-trials

Coronavirus

Hidden COVID virus found more than a year after infection

Pieces of the COVID virus can remain in blood and tissue, potentially leading to lingering post-infection issues.

Clinical trials are underway for therapies targeting the hidden virus in long COVID patients. [ more ]

Medscape

Cannabis for Psychiatric Disorders? Experts Weigh In

There is a growing belief that cannabis could be a good treatment for psychiatric disorders.

There is a lack of clinical trials and research on the use of cannabis as a treatment for psychiatric disorders. [ more ]

Medscape

Cannabis for Psychiatric Disorders? Experts Weigh In

There is a growing belief that cannabis could be a good treatment for psychiatric disorders.

There is a lack of clinical trials and research on the use of cannabis as a treatment for psychiatric disorders. [ more ]

Aspen Daily News

You Can Work from Home, You Can See a Doctor from Home...and Now You Can Participate in a Clinical Trial from Home

Fragile X Syndrome (FXS) is a rare neurological disease that affects 1 in 4,000 boys and 1 in 8,000 girls worldwide.

Former Congressman Gregg Harper's son has FXS and laments the lack of clinical research and FDA-approved therapies for the condition. [ more ]

The Berkshire Eagle

You Can Work from Home, You Can See a Doctor from Home...and Now You Can Participate in a Clinical Trial from Home

Fragile X Syndrome (FXS) is a rare neurological disease that is often misdiagnosed as autism or ADHD.

Former Congressman Gregg Harper's son has FXS and has been waiting for an FDA-approved therapy. [ more ]

WIRED

Dr. Ishwaria Subbiah Is Reimagining Cancer Care

Dr. Subbiah focuses on ensuring that every person has access to cancer clinical trials, regardless of their background or location.

Expanding access to clinical trials represents a paradigm shift in oncology, and convincing stakeholders of the value of equitable representation is a challenge for Dr. Subbiah. [ more ]

www.standard.co.uk

Ex-Premier League football scout given all-clear after pioneering cancer trial

Former Manchester United scout, Tom Critchley, has been given the all-clear from cancer thanks to a groundbreaking clinical trial.

The Aphrodite trial is investigating whether a higher dose of radiotherapy can treat rectal cancer without surgery.

Critchley urges other cancer patients to consider participating in clinical trials. [ more ]

www.cbc.ca

She survived stomach cancer. Now, she's helping fight the deadly disease | CBC News

Katy Kosyachkova was diagnosed with stomach cancer over a decade ago and founded My Gut Feeling to support stomach cancer patients and survivors.

Only 29% of those diagnosed with gastroesophageal (GE) cancers survive for at least five years, highlighting the need for advocacy and support.

My Gut Feeling has helped secure millions in grant money for research on gastroesophageal cancers, including funding for clinical trials of a promising drug. [ more ]

www.cbc.ca

She survived stomach cancer. Now, she's helping fight the deadly disease | CBC News

Katy Kosyachkova was diagnosed with stomach cancer over a decade ago and founded My Gut Feeling to support stomach cancer patients and survivors.

Only 29% of those diagnosed with gastroesophageal (GE) cancers survive for at least five years, highlighting the need for advocacy and support.

My Gut Feeling has helped secure millions in grant money for research on gastroesophageal cancers, including funding for clinical trials of a promising drug. [ more ]

www.npr.org

Testosterone is probably safe for your heart. But it can't stop 'manopause'

The FDA cautions that prescription testosterone is only approved for men who have low testosterone due to certain medical conditions.Wladimir Bulgar /Getty Images/Science Photo Libra In 2014 Time magazine ran a cover story titled Manopause?!, documenting the rise of the $2 billion testosterone industry, which marketed the hormone as a way to fend off age-related declines in sexual function, energy and strength.

Harvard Business Review

Business

Video Quick Take: Medidata's Anthony Costello on the Value of Decentralized Trials - SPONSOR CONTENT FROM MEDIDATA

Welcome to the HBR Video Quick Take.I'm Todd Pruzan, senior editor for Research and Special Projects at Harvard Business Review.A decentralized clinical trial, or DCT, is a method of conducting clinical trials in which part or all of the trial happens outside a traditional physical clinic or trial site.

moreback

participants

DATAVERSITY

10 months ago

Business intelligence

Leveraging AI and Automation to Streamline Clinical Trial Data Management - DATAVERSITY

Clinical trials are critical in developing and approving new medical treatments and technologies.These trials generate massive data that needs to be managed efficiently and accurately to ensure patient safety and successful research outcomes.The good news is that advances in AI and automation technology, such as AI-based data extraction, virtual clinical trials, and predictive analytics, are making it easier for clinical trial managers to streamline their clinical trial Data Management processes and gain insights that can help improve patient outcomes.

KQED

Science

Magic Mushrooms May Treat Depression. But Hurdles to Psilocybin Access Abound | KQED

"A lot of 'dones,' a lot of 'ols,'" she said.Some of them helped her sleep, but left her feeling numb.She recalled thinking, "I still feel sad, so what are we doing here, antidepressants?"Diamond was curious whether a clinically guided mushroom trip would help, and she enrolled in this clinical trial testing the safety and efficacy of psilocybin, the psychoactive ingredient in "magic mushrooms," for her type of bipolar depression.

time.com

FDA Approves First Pill for the Microbiome

Probiotics have long been star ingredients in dairy foods, drinks, and supplements, promising to generate a better bacterial balance to our guts.On Apr. 26, the U.S. Food and Drug Administration (FDA) took a step toward formalizing the idea of adjusting gut-bacteria populations when it approved the first oral drug designed to treat the microbiome.

www.cnn.com

Blood sugar drug tirzepatide also leads to substantial weight loss in diabetes patients, Eli Lilly says

There's more evidence that the injectable drug tirzepatide helps people with diabetes lose weight as well as control their blood sugar, according to the drug's manufacturer, Eli Lilly and Company.In a new study, more than 900 adults with obesity and diabetes took the drug for a year and five months, and those on the highest dose lost an average of 34 pounds, or nearly 16% of their starting weight.

www.aljazeera.com

China approves first domestic mRNA COVID-19 vaccine

In a study of 4,000 participants, the vaccine showed efficacy of 85.3 percent 14 to 28 days after a booster vaccination.China has approved its first domestically developed mRNA vaccine against COVID-19, its manufacturer said on Wednesday, months after the relaxation of strict zero-COVID regulations sparked a surge in cases.

Inverse

A Promising Covid-19 Antiviral Cuts Hospitalizations in Half - Will Americans Get It?

It would seem with dwindling viral cases, millions of vaccines deployed, and an end to a public health emergency that, Covid-19 is finally petering out.On the contrary, the virus is here to stay, much like the seasonal flu.While vaccines have been shown to prevent the majority of severe cases, there's still only one effective and federally approved therapeutic, called Paxlovid, which has to be taken within five days of symptoms to be effective.

www.nytimes.com

How to Treat Postpartum Depression

In recent years, mental health struggles have become the leading cause of maternal mortality in the United States, primarily due to suicides and drug overdoses.It is estimated that one in eight new moms experience postpartum depression, and some research has suggested that the prevalence climbed to as high as one in three during the early days of the pandemic.

www.cnn.com

Men with advanced prostate cancer missing months of therapy' amid medication shortage

Doctors across the United States who treat people with advanced prostate cancer can't find supplies of a medicine that may help them live longer.Pluvicto, a drug to treat metastatic castration-resistant prostate cancer, also known as mCRPC, is in such short supply that its maker, Novartis, said it cannot allow further supply until it can produce more of the drug.

www.cnn.com

Mediterranean diet may lower heart disease risk in women by nearly 25%, study finds | CNN

Editor's Note: Sign up for CNN's Eat, But Better: Mediterranean Style.Our eight-part guide shows you a delicious expert-backed eating lifestyle that will boost your health for life.Closely following a Mediterranean diet may cut a woman's risk of heart disease and death by nearly 25%, according to a new analysis of 16 studies.

Washington Post

Europe news

With Russia's Viagra supply cut off, authorities look to generics as backup

Shipping containers are reshuffled and stored at a commercial port in Vladivostok, Russia, on Wednesday.(Tatiana Meel/Reuters)Russia's Industry and Trade Ministry said Wednesday that it had taken steps to establish domestic production of generic forms of Viagra, the erectile dysfunction remedy, after the U.S. manufacturer of the drug halted supplies.

www.theguardian.com

What are the real signs of a healthy gut? A user's guide

The gut, or gastrointestinal system, is the long and winding route that food and drink takes through the body.It ensures that all the beneficial nutrients are absorbed and used for energy, growth and repair.You can think of it as a number of hollow organs connected by a tube which starts at the mouth and ends at the anus.

www.nytimes.com

The Subversive Wisdom of Old Wives' Tales'

As a kid, I believed every last old wives' tale.I was sure that if I read in the dark I would go blind.That if I swam in the lake after a generous lunch I might sink to the bottom.That if I swallowed my bubble gum, the kind that came with a tiny comic strip, the hardened pebble of it would ferment in my stomach for the next seven years, which was a whole lifetime to me then.

Patently-O

Intellectual property law

Public use == "accessible to the public."

by Dennis Crouch
Bottom line in this new Minerva case - file your patent application before bringing a new product to a trade show.The Old Case: The battle between Hologic and Minerva went to the US Supreme Court in 2021; with the Court retained the doctrine of assignor-estoppel that bars a patent assignor from later challenging the patent's validity or enforceability.

Fatherly

Fathers

This Genius Wearable Helps Your Body Break The Fight-Or-Flight Response For Less Stress & Better Sleep

Most dads aren't living the monk life.Instead, you're weighed down with the responsibilities of raising kids and building careers when you would probably rather be finding nirvana a different way.While staying physically active often helps manage the stress that comes with the job, technology like the Apollo can help you rebalance your nervous system over time without you ever lifting a finger.

Futurism

Scientists About to Test Medicine to Grow New Teeth

Japanese scientists to start clinical trials for regrowing teeth using antibody treatment to deactivate USAG-1 protein.

Hope to provide a 'third option' for those with missing teeth alongside implants and dentures.

Success in animal testing provides optimism for regrowing teeth in humans. [ more ]

www.theguardian.com

1 week ago

Cost of developing new drugs may be far lower than industry claims, trial reveals

The true cost of developing medicine may be far less than estimated by the pharmaceutical industry, sparking the need for transparency in clinical trial spending. [ more ]

Miami Herald

3 weeks ago

Blasting cancer with 120 drugs? How FIU and a Miami-area children's hospital tried it

Mary's timely birth and bone marrow match saved her brother Logan's life from leukemia.

A clinical trial at Nicklaus Children's Hospital with FIU utilized a personalized approach to test cancer cells against 120 drugs. [ more ]

ABC7 San Francisco

ALS drug will be pulled from US market after study showed patients didn't benefit

Patients won't benefit from failed Lou Gehrig's disease drug, leading to its withdrawal from the market.

Only three ALS medicines left for U.S. patients, with one showing survival extension by several months. [ more ]

Nature

TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers - Nature

Antibody and CAR T cell therapies show promise in treating T cell cancers

Development of antibody-drug conjugate to target TRBC1 shows potential for improved outcomes [ more ]

National Cancer Institute

NCI Launches Virtual Clinical Trials Office

Addressing decline in cancer clinical trial participation

Establishing NCI Virtual Clinical Trials Office to provide centralized support [ more ]

www.nytimes.com

Study Suggests Genetics as a Cause, Not Just a Risk, for Some Alzheimers

A new genetic classification could identify up to a fifth of Alzheimer's patients with a known genetic cause, potentially leading to more targeted treatments. [ more ]

Ars Technica

OMG science

Biogen dumps dubious Alzheimer's drug after profit-killing FDA scandal

Biogen is abandoning its Alzheimer's drug Aduhelm and terminating all development and commercialization activities.

The drug failed two Phase 3 trials and has faced controversy over its regulatory approval and pricing. [ more ]

moreOMG science

TNW | Deep-Tech

6 days ago

European startups

Dutch startup to bring robotic blood drawing to hospitals

Vitestro secured â¬20mn funding for robotic blood drawing device, focusing on improving patient experience and addressing healthcare personnel shortages. [ more ]

time.com

4 weeks ago

Most Cancer Drugs Granted Accelerated FDA Approval May Not Work

Most cancer drugs granted accelerated approval do not demonstrate benefits within five years.

FDA's accelerated approval program allows early access to promising drugs for fatal diseases, but with the tradeoff of potential unproven effectiveness. [ more ]

www.nytimes.com

Will Superfood Powders' Actually Make You Healthier?

You've probably noticed ads for these superfood powders scattered across social media or on your favorite podcast.Athletic Greens, Daily Greens, Supergreens mix just one scoop of these multivitamin powders into a glass of water or a shake, their marketing typically says, and you can get all of the vitamins and minerals you need for the day, as well as added health benefits like a stronger immune system, less stress, better digestion and more energy.

www.nytimes.com

Psychedelics Are a Promising Therapy, but They Can Be Dangerous for Some

When Dr. Charles Nemeroff first met his patient, the 32-year-old woman had already been to see several psychiatrists.Initially, the woman, whose identity has been concealed to protect her privacy, had experienced paranoid and racing thoughts, insisting there were listening devices in her phone and that people were watching her; she even sold her home in an attempt to get away from them.

time.com

Women in technology

Why Heart Disease Research Still Favors Men

Women are more likely to die from heart attacks due to medical system neglect.

Clinical trials for medications often exclude women, leading to gaps in identifying effective treatments. [ more ]

www.france24.com

France news

Medical cannabis could soon get the green light in France after unprecedented trial

Patients find relief from chronic pain through prescribed medical cannabis in French trial.

First results of the trial indicate significant symptom improvement with no unexpected side effects. [ more ]

www.france24.com

France news

French researchers slam former hospital director for 'unauthorised' Covid trial

French medical bodies on Sunday called on authorities to punish researcher Didier Raoult for "the largest 'unauthorised' clinical trial ever seen" into the use of hydroxychloroquine to treat Covid-19.Issued on: 28/05/2023 - 17:39 2 min A picture taken on February 26, 2020 shows French professor Didier Raoult, biologist and professor of microbiology, specialized in infectious diseases and director of IHU Mediterranee Infection Institute posing in his office in Marseille, southeastern France.

www.theguardian.com

Coronavirus

People assume you're crazy for doing it': the Melbourne clinic infecting healthy patients

Human challenge trials are efficient for evaluating vaccines and therapeutics.

Controlled studies like Chim can provide reliable insights into diseases and immunity.

DCT in Australia aims to accelerate the vaccine approval process and benefit financially. [ more ]

Nature

Coronavirus

Speed up relief for long COVID through grassroots clinical trials

Clinical trials for long COVID are challenging and require large academic centers.

Diagnostic biomarkers and effective therapies are urgently needed for long COVID. [ more ]

Nature

Artificial intelligence

How AI is being used to accelerate clinical trials

Computing power followed Moore's law, but drug development has its own pace with Eroom's law. Clinical trials are lengthy, costly, and only few drugs get approval in the end. [ more ]

Medium

Artificial intelligence

These Companies are Changing Biotech & Biopharma with AI in 2024

AI is revolutionizing the BioTech & BioPharma space by accelerating drug discovery and development processes.

Companies like Insilico Medicine and Exscientia are using AI platforms to design and optimize drug candidates, leading to faster timelines and more efficient drug development. [ more ]

Nature

A spotlight on the stark imbalances of global health research

The United States leads in high-quality output in health sciences research.

Harvard University dominates in the field of health sciences. [ more ]

ABC7 San Francisco

4 months ago

Breast cancer vaccine now in early clinical trials: What to know

A new vaccine being studied in early clinical trials may hold the potential to help some women with breast cancer.

The vaccine targets triple-negative breast cancer, the most aggressive and deadliest form of breast cancer. [ more ]

www.dw.com

Marburg in Equatorial Guinea: Symptoms of a deadly virus DW 02/16/2023

The West African country Equatorial Guinea is experiencing its first-ever outbreak of Marburg fever.At least nine people had died from the highly contagious viral disease, said the World Health Organisation (WHO) in a statement on February 13.There were a further 16 suspected cases, involving symtoms such as fever, fatigue, diarrhea and vomiting.

undark.org

Why Children's Medications Are Not Fully Tested

Limited pediatric drug research leaves children at risk of off-label prescriptions.

Physicians and parents face challenges due to lack of pediatric clinical trials. [ more ]

News Center

New Drug Shows Promise for Treating Rare Brain Tumors - News Center

An experimental drug, dordaviprone, shows promise in treating H3 K27M-mutant diffuse midline gliomas.

The study revealed a 30% positive response rate to the drug in patients with this rare brain tumor subtype. [ more ]

Nature

This 'super gonorrhoea' drug holds a lesson for avoiding microbial armageddon

New antibiotics and antifungal drugs show promise in fighting drug-resistant infections

Non-profit organizations play a crucial role in developing and bringing new drugs to the market [ more ]

time.com

The Unique Hell of Getting Cancer as a Young Adult

New cancer cases in young adults have surged 79% over three decades in the U.S.

There is a need to study factors contributing to earlier onset cancers for better treatments. [ more ]

Nature

CAR T therapy for multiple sclerosis enters US trials for first time

CAR T cells are being used in US trials for multiple sclerosis and other autoimmune disorders.

CAR T cells show potential to provide more effective treatment for autoimmune diseases like multiple sclerosis. [ more ]

National Cancer Institute

NCI Launches Cancer Screening Research Network

The NIH launched the Cancer Screening Research Network (CSRN) to evaluate emerging technologies for cancer screening.

The network will focus on identifying cancers earlier to enhance treatment outcomes and extend lives. [ more ]

News Center

Rethinking the Burden of Cancer Treatments' Side Effects - News Center

Even mild and moderate side effects can lead to cancer patients discontinuing treatment.

Patient-reported perspectives on side effects are crucial for understanding treatment tolerability. [ more ]

Axios

FDA approval of cancer treatment provides new weapon against tumors

CAR-T therapy is successful in some blood cancers but not yet approved for solid tumors. Tumor-Infiltrating Lymphocytes (TIL) use immune cells from a patient's tumor for treatment. [ more ]

www.nytimes.com

The Race Is On to Stop Ozempic Muscle Loss

Luxury gyms and nutritionists are catering to individuals taking weight loss medications by offering specific programs and meal plans to counteract muscle loss.

Drug companies like Eli Lilly are partnering with other companies to develop combination treatments that help patients lose fat while preserving or gaining muscle. [ more ]

time.com

An Experimental Weight-Loss Drug Shows Lasting Results in Early Study

Amgen's experimental weight-loss shot, MariTide, appears to keep weight off even after patients stop taking it.

MariTide is an antibody-drug conjugate that blocks the GIP receptor and mimics a gut hormone called GLP-1. [ more ]

www.esquire.com

Research Into Alzheimer's Therapy Limited By Lack of Attention to Black Patients

The latest therapies for Alzheimer's Disease show promise but face challenges in reaching all those who need them.

Participants in clinical trials for Alzheimer's drugs are disproportionately White, raising questions about the effectiveness for people of color. [ more ]

www.independent.co.uk

New ground-breaking' bowel cancer vaccine to go on trial at hospital

A potentially ground-breaking vaccine to treat early bowel cancer is set to go on trial in England and Australia.

The vaccine will be administered to patients before surgery in the hopes of causing the body to attack the cancer and making surgery less invasive.

The trial will be run by the Cancer Research UK Southampton Clinical Trials Unit and will enroll 44 patients over an 18 month period. [ more ]

Los Angeles Times

Los Angeles

A California panel is holding up studies on psychedelics. Some researchers want it gone

Researchers at the Pacific Neuroscience Institute in Santa Monica are unable to enroll patients in clinical trials due to a hold placed on their studies by a government panel.

The Research Advisory Panel of California, established over 50 years ago, has the power to reject poorly conceived studies and monitor ongoing research involving restricted drugs and addiction treatment. [ more ]

AdExchanger

Marketing tech

A Healthy Dose Of Programmatic, With Doceree's CEO | AdExchanger

The US and New Zealand are the only two countries that allow pharmaceutical companies to advertise prescription drugs directly to consumers.

Doceree is a programmatic healthcare marketing platform that allows brands to target doctors with secure, real-time messages on physician-only platforms. [ more ]

Medscape

Mental health

Cannabis for Psychiatric Disorders? Experts Weigh In

There is a growing belief that cannabis could be a good treatment for psychiatric disorders.

There is a lack of clinical trials and research on the use of cannabis as a treatment for psychiatric disorders. [ more ]

www.theguardian.com

Mental health

Beyond the evidence': media reports overhype ketamine's use as a depression treatment, review finds

1. Media reports have significantly overstated the efficacy of ketamine in treating depression, according to a recent review of the evidence.

2. While there have been some promising results in clinical trials, the review concluded that more research is needed to determine whether ketamine is an effective treatment for depression.

3. The review also highlighted the need for doctors and other healthcare professionals to be mindful of the potential harms associated with ketamine use, particularly in the absence of robust evidence of [ more ]

ABC7 San Francisco

4 months ago

Breast cancer vaccine now in early clinical trials: What to know

A new vaccine being studied in early clinical trials may hold the potential to help some women with breast cancer.

The vaccine targets triple-negative breast cancer, the most aggressive and deadliest form of breast cancer. [ more ]

ABC7 San Francisco

4 months ago

Breast cancer vaccine now in early clinical trials: What to know

A new vaccine being studied in early clinical trials may hold the potential to help some women with breast cancer.

The vaccine targets triple-negative breast cancer, the most aggressive and deadliest form of breast cancer. [ more ]

www.npr.org

WHO says we can 'write the final chapter in the story of TB.' How close are we?

The head of the World Health Organization wants to eradicate tuberculosis, one of the oldest and deadliest diseases.

Two clinical trials have shown that taking levofloxacin, an antibiotic commonly used for drug-resistant TB, can reduce the risk of developing drug-resistant strains by about 60%.

The new data could inform global TB guidelines in the future. [ more ]

www.npr.org

WHO says we can 'write the final chapter in the story of TB.' How close are we?

The head of the World Health Organization wants to eradicate tuberculosis, one of the oldest and deadliest diseases.

Two clinical trials have shown that taking levofloxacin, an antibiotic commonly used for drug-resistant TB, can reduce the risk of developing drug-resistant strains by about 60%.

The new data could inform global TB guidelines in the future. [ more ]

www.npr.org

FDA advisers endorse new RSV antibody drug for babies

RSV is a seasonal virus that lands tens of thousands of young children in the hospital every year.On Thursday, advisors to the FDA voted in favor of approving a long-acting antibody that protects infants from RSV. Christoph Soeder/Picture Alliance via Getty Images A panel of advisers to the Food and Drug Administration have recommended that the agency approve a new antibody drug to protect infants from serious lung illnesses caused by respiratory syncytial virus, also known as RSV.

www.independent.co.uk

Plan for GPs to offer controversial celebrity weight loss jab

Rishi Sunak said using new drugs to combat obesity could be a game-changer as he announced a 40m pilot scheme to increase access to specialist weight management services.The government wants to tackle the health problems and 6.5bn cost to the NHS of obesity by making it easier to access weight-loss treatments through GPs.

www.independent.co.uk

New drugs to combat obesity a game changer' as 40m pilot scheme launched

www.independent.co.uk

Life sciences sector to get 650m war chest' in new funding package

A shake-up of planning rules to free up lab space and efforts to encourage pension schemes to invest in emerging science and technology firms will all form part of a new 650m funding package for the UK's life sciences sector.Announced by chancellor Jeremy Hunt, the life sciences war chest is the latest government effort to follow up on the prime minister's pledge to turn the UK into a science superpower.

www.independent.co.uk

What the papers say May 26

The Immigration debate was the focus for the majority of Britain's newspapers on Friday.The Guardian revealed Home Secretary Suella Braverman's plan to deport 3,000 asylum seekers a month.The Mirror says ministers have been accused of losing control on immigration after figures hit a record high last year.

www.independent.co.uk

Lack of evidence on antidepressants for chronic pain, say experts

Hundreds of thousands of people in the UK are being prescribed antidepressants for chronic pain without sufficient evidence they work, researchers have said.In the largest study of its kind, experts looked at medicines commonly prescribed on the NHS including amitriptyline, duloxetine, fluoxetine (Prozac), citalopram, paroxetine (Seroxat) and sertraline.

www.independent.co.uk

Large-scale trials needed to test anti-ageing supplements, expert says

Anti-ageing supplements need to be clinically tested, but the answer to a longer healthy life may already be available, an expert has said.Professor Cynthia Kenyon, an expert in ageing and longevity, said that while many supplements are easily accessible and inexpensive, there is little evidence to show they are effective.

Patently-O

Intellectual property law

Guest Post: Jillian Grennan, Charting New Paths in Innovation: Reflections from Harvard's Innovation Economics Conference

(Editor's note: (This post is part of a series by the Diversity Pilots Initiative, which advances inclusive innovation through rigorous research.The first blog in the series is here, and resources from the first conference of the initiative are available here.-Jason) By: Jillian Grennan, Associate Professor of Finance and Principal, Diversity Pilots Initiative Recently, I had the privilege of being part of the Junior Innovation Economics Conference at Harvard Business School.

IPWatchdog.com | Patents & Intellectual Property Law

Intellectual property law

Federal Circuit Clarifies Public Use Bar Requirements in Win for Hologic Against Minerva

"AAGL 2009 was the 'Super Bowl' of the industry and was open to the public.It included attendees who were critical to Minerva's budding business-such as potential investors and physicians-and Minerva had every incentive to showcase the Aurora devices to these attendees as best as it could."

KQED

Healthcare

'Screaming Into a Void': Long COVID Patients Have Waited in Vain for Years for Treatments | KQED

Dr. Steven Deeks, an infectious disease specialist at UCSF who has extensively researched long COVID, argues that clinical trials for possible treatments should have started months ago."Based on the fact there's anecdotes of people getting better with antiviral therapy, yes, it's an absolute urgency right now to study, in a controlled manner, all of the antiviral therapies that we have available," he said.

KQED

California

California Food Banks See Major Spike In Demand | KQED

California's food banks are reporting alarming spikes in demand, that's according to the state's association of food banks, which says the end of pandemic-era food benefits and record high inflation is to blame.In April, the Sacramento food bank and its partners fed 281,000 people - almost double the amount it served before the pandemic.

www.nytimes.com

World politics

The Evidence for Therapy

Millions of Americans go to talk therapy.But does it work?It's a surprisingly difficult question to answer.Talk therapy does produce great benefits for some people, but not for everyone, so it might not work for you, my colleague Susan Dominus wrote for The New York Times Magazine's therapy issue, published this week.

www.nature.com

Science

How One Man's Rare Alzheimer's Mutation Delayed the Onset of Disease

Researchers have identified a man with a rare genetic mutation that protected him from developing dementia at an early age.The finding, published on 15 May in Nature Medicine, could help researchers to better understand the causes of Alzheimer's disease and potentially lead to new treatments.For nearly 40 years, neurologist Francisco Lopera at the University of Antioquia in Medellin, Colombia, has been following an extended family whose members develop Alzheimer's in their forties or earlier.

www.npr.org

Science

Why genetic engineering experts are putting a spotlight on Victoria Gray's case

A MARTINEZ, HOST: Some of the world's most celebrated experts on genetic engineering are in London this week to debate the promise and the peril of gene editing.Yesterday, the summit put the spotlight on one person, Victoria Gray.The Mississippi woman was the first person with sickle cell disease to be treated with a gene-editing technique known as CRISPR.

Harvard Business Review

Business

Video Quick Take - Parexel's Jonathan Shough on Digital Transformation - SPONSOR CONTENT FROM PERSISTENT

Welcome to the HBR Video Quick Take.I'm Todd Pruzan, senior editor for research and special projects at Harvard Business Review.We're here today with Jonathan Shough, chief information officer at Parexel, one of the world's largest clinical research organizations.Jonathan has more than 30 years of IT experience, and he joined Parexel in November 2022 to drive the development of innovative technologies and solutions to meet customer needs in a constantly evolving and growing clinical trial landscape.

www.thelocal.fr

France politics

Macron says France to train Ukrainian fighter pilots

Emmanuel Macron on Monday announced 13 billion of new foreign investment in France through the Choose France project - an initiative that aims to make France a more attractive place for foreign businesses.Here are the sectors where big new investments have been announced.Published: 15 May 2023 15:18 CEST Macron on Monday attended the 6th annual Choose France conference at Versailles one of his pet projects which is central to his vision of making France a more business-friendly country.

www.thelocal.fr

France politics

E-batteries, solar panels and medicines: France announces 13 billion of new foreign investment

Macron on Monday attended the 6th annual Choose France conference at Versailles one of his pet projects which is central to his vision of making France a more business-friendly country.The Elysee's figures released on Monday show 13 billion of investment via Choose France only one part of the foreign direct investment in France.

www.nytimes.com

Girls

What to Know About the New Treatment for Hot Flashes

The Food and Drug Administration approved a new nonhormonal oral drug Friday, under the brand name Veozah, designed to treat menopausal hot flashes.The drug provides women with a safe and effective treatment option, Dr. Janet Maynard, director of the F.D.A. Office of Rare Diseases, Pediatrics, Urologic and Reproductive Medicine said in a statement.

www.cnn.com

FDA green lights a new type of drug for menopausal hot flashes

The US Food and Drug Administration on Friday approved a new type of drug to treat hot flashes and night sweats during menopause.Veozah, or fezolinetant, made by Astellas Pharma, is the first neurokinin 3 (NK3) agonist.It blocks receptors in the brain that play a role in the regulation of body temperature.

TODAY.com

Identical triplet sisters all became OB-GYN doctors ... and work with their mom!

Identical triplets Joanna, Vicky and Sarah Bedell were 8 years old the first time they saw their mom, Dr. Janet Gersten, deliver a baby.Now 36, Vicky recalls standing off "to the side against a wall," and how the patient kept apologizing for cursing."I remember my mom being very collected and having confident control of the situation, which was very cool to watch," Sarah told TODAY's Sheinelle Jones, in an interview before their May 12 appearance on TODAY.

www.cnn.com

Novo Nordisk limits Wegovy doses for new patients as demand outpaces supply

Novo Nordisk, maker of the weight-loss drug Wegovy, said it would limit supply of starter doses as demand outpaces the company's manufacturing capacity.The supply interruptions aren't expected to affect higher doses of the medicine for people who already take the drug, the company said in a statement posted Thursday on its Wegovy website.

www.cnn.com

Up to 60% of stroke survivors may develop cognitive decline within a year

Up to 60% of all stroke survivors develop memory and thinking problems within a year, and one-third go on to develop dementia within five years, according to a new American Stroke Association scientific statement.The numbers are staggering, right? said Dr. Andrew Freeman, director of cardiovascular prevention and wellness at National Jewish Health in Denver.

www.cnn.com

Johnson & Johnson halts development of RSV vaccine in midst of late-stage clinical trials

Janssen, the pharmaceutical division of the Johnson & Johnson companies, announced Wednesday that it will scrap development of a vaccine for respiratory syncytial virus, or RSV, in adults.The company was in late-stage clinical trials of a vaccine to prevent lower respiratory tract disease in adults over the age of 60 with RSV.

www.independent.co.uk

Patients with incurable cervical cancer to be offered new drug

Patients with incurable cervical cancer are to be offered a new treatment which could give them more time with their loved ones.Keytruda, an immunotherapy drug manufactured by Merck Sharp and Dohme (MSD), is the first new treatment in 14 years approved to treat advanced cervical cancer.It is expected that over the next three years around 400 patients will benefit from the treatment, also known as pembrolizumab.

time.com

Researchers Are Getting Closer to Learning How to Treat and Prevent Long COVID

Three years into the COVID-19 pandemic, with millions of people around the world suffering from long-term complications of the virus, there is still no proven way to treat or prevent Long COVIDbesides not getting infected in the first place.Recently, however, there's been reason for cautious optimism.

www.cnn.com

Paxlovid not linked to Covid-19 rebound, FDA says ahead of meeting to consider drug's full approval

As the US Food and Drug Administration's independent advisers prepare to discuss Thursday the full approval of Pfizer's Covid-19 antiviral, Paxlovid, agency experts said this week that clinical trial data shows that it is safe and effective for treatment of mild to moderate illness in high-risk adults.

www.cnn.com

Drug-free relief from chronic constipation may come from a new vibrating pill

(CNN)People who struggle with chronic constipation have a new drug-free option to help get things moving again.It's a first-of-its-kind capsule about is the size of a regular pill -- but instead of releasing medication after it's swallowed, it vibrates to stimulate the colon.The capsules, called Vibrant, was cleared by the US Food and Drug Administration in August but just became available for doctors to prescribe this week.

Acm

Digital life

Researchers Develop Tool to Identify Existing Drugs to Use in Future Outbreak

An artificial intelligence algorithm developed by a global team led by researchers at New York University (NYU) can identify existing drugs that could be repurposed during future pandemics.The PHENotype SIMulator (PHENSIM) simulates tissue-specific infection of SARS-CoV-2 host cells and calculates the antiviral effects of existing drugs via in silico experiments that take into consideration selected cells, cell lines, and tissues under various alterations of biomolecules.

www.independent.co.uk

MP accuses NHS of abandoning sister' over brain cancer treatment

Sign up for the View from Westminster email for expert analysis straight to your inbox Get our free View from Westminster email An MP has accused the NHS of abandoning her sister who suffers from brain cancer in an emotional speech in parliament.Labour's Siobhain McDonagh fought back tears as she raised the experiences of 61-year-old Margaret McDonagh, a former Labour general secretary who sits in the House of Lords as Baroness McDonagh.

Boston.com

Boston

SmartLabs to convert entire third floor of CambridgeSide mall into lab space

Local Boston-based lab service provider SmartLabs signed the 140,000-square-foot lease, increasing their Greater Boston footprint by 75%.Boston-based lab space provider SmartLabs will convert the third floor of the CambridgeSide mall into lab space by late 2024.The health-science company signed the 140,000-square-foot lease as an expansion of its labs-as-a-service network, which provides "fractionalized access" to lab spaces.

Dezeen

Design

Respiray develops air-purifying collar for allergy sufferers

Health tech company Respiray has launched a wearable air purifier designed to fend off allergens by creating a "bubble of clean air" around the user's face.Worn around the neck like a collar, Respiray's Wear A+ device filters out irritants such as pet dander, dust, pollen and mould, and instead blows clean air towards the wearer.

BBC News