#car-t-cells
#car-t-cells

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www.nature.com

Scientists Found a Way to Supercharge Cancer-Fighting Cells

Bioengineered CAR T cells can be rejuvenated by engineering high levels of a specific protein, resembling stem cells, enhancing cancer-fighting abilities. [ more ]

Nature

FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy - Nature

CAR T cells tend to terminally differentiate in the solid tumour microenvironment due to chronic antigen stimulation.

Less-differentiated CAR T cells with CD45RA+CD62L+ phenotype persist longer and have greater self-renewal capacity for improved tumour control. [ more ]

Nature

CAR T cells can shrink deadly brain tumours - though for how long is unclear

Early studies show promising results against aggressive brain cancers with engineered immune cells.

CAR T cells could be modified to treat a wider range of cancers beyond blood cancers like leukaemia. [ more ]

Nature

CAR T therapy for multiple sclerosis enters US trials for first time

CAR T cells are being used in US trials for multiple sclerosis and other autoimmune disorders.

CAR T cells show potential to provide more effective treatment for autoimmune diseases like multiple sclerosis. [ more ]

Nature

Daily briefing: First private Moon lander makes history

Odysseus, built by Intuitive Machines, made it safely to the Moon

CAR T cell trials for MS treatment have started

Global project to gather DNA from world's lakes [ more ]

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