Cancer
fromNature
1 week agoBespoke DNA vaccine offers hope for treatment of notorious brain cancer
A personalized vaccine safely stimulates immune systems to attack glioblastoma tumors.
CNS Pharmaceuticals ( NASDAQ:CNSP) is back on every biotech watchlist after a 242.36% one-week ramp tied to its Berubicin glioblastoma story. But here's what you should actually be watching. Holders captured the move; new entrants face tougher math from here. The market cap sits at roughly $6.36 million, the company reported a Q1 2024 net loss of $3.50 million with cash collapsed to about $800,000, and the stock is still off 42.18% over one year and effectively 100% over five years on a split-adjusted basis.
“I'm a 34-year-old NBA center,” Mr. Collins wrote in April 2013. “I'm black. And I'm gay.” The statement was both unsentimental and seismic. In a sports culture that had long treated homosexuality in male locker rooms as taboo, Mr. Collins became the first openly gay man on a major professional American team sport. In breaking a barrier that had stood for generations, he transformed from a largely anonymous role player into a historic figure.
Debbie lived fully, authentically, and with purpose. When she was diagnosed with brain cancer, she adopted the motto "no day but today," inspired by one of her favorite musicals, "Rent." While going through treatment, she wrote, read, traveled, danced, exercised, baked, ate what she wanted, and cherished her time with family and her large circle of friends, all of whom loved her distinctive laugh.
Experiments show that many brain tumours called glioblastomas grab serine, a crucial amino acid, from their environment rather than synthesizing it themselves: a metabolic Achilles' heel. The scientists fed mice with certain kinds of glioblastoma a diet that lacked serine and found that the rodents' tumours, unable to get their fix the usual way, grew more slowly. The animals also lived longer.
In recent videos posted to a now-private TikTok account, Emily Long spoke candidly about her husband's treatment for the aggressive brain cancer glioblastoma, including his seizures, increased irritability, and struggle to find the right regimen of medications.
Glioblastoma tumors exhibit dramatic variations in their genetic makeup and structure across different regions, complicating treatment efforts and emphasizing their treatment-resistant characteristics.