#als

#als

Investigators discovered that a genetic mutation in the RNA-binding protein Ataxin-2 (ATXN2) disrupts the stability of microtubules - central components of the cytoskeleton in motor neurons - leading to impaired neuron growth and function. The findings may help inform the treatment of amyotrophic lateral sclerosis (ALS), which progressively destroys motor neurons and leads to muscle weakness and paralysis.

I wrote them letters for special days because I asked people who had lost parents what they wanted most from them. I'd write a sentence and sob. But little by little, sometimes at 3 a.m., I wrote them. For weddings, pregnancies, graduations, the first and last day of school. I even wrote one for a grandchild I may never have.

We are best of friends. We are really close. We are great co-parents. We really figured out the formula to staying a family and I think our kids are benefiting greatly from it and we are as well.