Researchers have developed advanced gene delivery tools that can activate genes in various brain and spinal cord cell types, aiming to treat neurodegenerative diseases like ALS, Parkinson's, and Alzheimer's. This breakthrough, achieved through the BRAIN initiative by over 300 scientists, enhances our understanding of neural cell interactions and how diseases disrupt these processes. With ongoing investment, experts believe this innovation could transform our approach to studying consciousness and treating previously incurable neurological disorders, directly impacting the lives of millions afflicted by these diseases.
Scores of researchers have produced new tools that can deliver genes and selectively activate them in hundreds of different cell types in the brain and spinal cord.
This will revolutionize both our grasp of how the brain works and our ability to treat currently intractable conditions.
The advancement of the gene delivery systems, the result of several years' work by more than 300 U.S. and international scientists, was described in eight papers.
Neurodegenerative diseases afflict more than 9 million Americans, highlighting the urgent need for effective therapies.
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