#cancer-immunotherapy

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#car-t-cell-therapy #solid-tumors #mrna-vaccines #regulatory-t-cells #peripheral-immune-tolerance
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fromenglish.elpais.com
1 day ago
Medicine

A living drug manages to eliminate tumors in mice with pancreatic, ovarian and kidney cancer

An ultrasensitive CAR-T cell therapy successfully eliminated solid tumors in laboratory mice by targeting the CD70 protein at previously undetectable levels.
fromNature
2 days ago
Medicine

Ultra-sensitive CAR T cells eliminate hard-to-treat tumours in mice

Engineered immune cells detecting extremely low CD70 antigen levels successfully eliminated solid tumors in mice, overcoming previous CAR-T therapy limitations by targeting antigens previously considered undetectable.
more#car-t-cell-therapy
Science
fromScienceDaily
1 month ago

Vitamin A may be helping cancer hide from the immune system

Retinoic acid signaling in cancer cells and dendritic cells suppresses anti-tumor immunity, and blocking this pathway restores vaccine effectiveness.
Science
fromFast Company
1 month ago

Scientific breakthroughs are redefining what's possible with asteroids, cancer research, and neurotech

Cross-disciplinary collaborations and AI enable breakthroughs—asteroid deflection, immunotherapy mapping, and vestibular control—advancing capability to protect and improve human life.
Medicine
fromNature
2 months ago

Transient hepatic reconstitution of trophic factors enhances aged immunity - Nature

Replenishing thymus-derived factors (DLL1, FLT3-L, IL-7) via liver-expressed mRNA restores immune function in aged mice, improving vaccine and cancer immunotherapy responses.
#mrna-vaccines
fromwww.scientificamerican.com
3 months ago
Cancer

How mRNA Cancer Vaccines Could Treat Pancreatic and Other Types of Cancer

mRNA vaccines are being developed as therapeutic cancer treatments, showing promise where traditional therapies often fail, especially for hard-to-treat cancers like pancreatic cancer.
fromwww.aljazeera.com
4 months ago
Medicine

Could COVID-19 mRNA vaccines also fight cancer?

mRNA vaccines can stimulate immune responses that help the body recognize and attack cancer, enabling potential off-the-shelf cancer vaccines and improving patient survival.
more#mrna-vaccines
Medicine
fromFast Company
4 months ago

2025 Nobel Prize in Medicine paves way for possible new cancer treatments

Regulatory T cells prevent immune attacks on healthy tissue, enabling new research and therapies for autoimmune diseases and cancer.
Medicine
fromwww.npr.org
4 months ago

The medicine Nobel Prize goes to 3 scientists for work on peripheral immune tolerance

Discoveries by Brunkow, Ramsdell and Sakaguchi revealed mechanisms of peripheral immune tolerance, enabling therapies for cancer, autoimmune disease, and improved transplants.
Medicine
fromwww.bbc.com
4 months ago

Nobel Prize for discovering immune security guards

Discovery of immune 'security guards' that remove self-reactive immune cells explains self-tolerance and enables new autoimmune and cancer therapies.
Science
fromwww.post-gazette.com
5 months ago

Common artificial sweetener linked to worse cancer treatment outcomes in Pitt study

Sucralose may impair cancer immunotherapy effectiveness by disrupting the gut microbiome and associated immune responses.
fromNews Center
7 months ago

Mitochondria Support T-cells Proliferation and Memory Formation - News Center

Investigators led by Navdeep Chandel, PhD, have demonstrated that mitochondrial metabolism is crucial for T-cell proliferation and the prevention of T-cell exhaustion in cancer and chronic infection.
Science
Health
fromHarvard Gazette
7 months ago

Road to game-changing cancer treatment - Harvard Gazette

Cancer immunotherapies harness patients' immune systems, revolutionizing treatment outcomes and improving survival rates for various cancer types.
Cancer
fromNature
7 months ago

Microbiota-driven antitumour immunity mediated by dendritic cell migration - Nature

Immune checkpoint blockade therapies significantly improve cancer survival but have low complete response rates, necessitating new biomarkers and strategies.
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