"The Nobel Prize in Physiology or Medicine 2025 has been awarded for discoveries that explain how the immune system attacks hostile infections, but not the body's own cells. The prize is shared by Japan's Shimon Sakaguchi and US researchers Mary Brunkow and Fred Ramsdell. They discovered "security guards" that eliminate parts of the immune system that could attack the body. Their work is being used to develop new treatments for autoimmune diseases and cancer."
"The winners share a prize fund worth 11m Swedish kronor (870,000). "Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases," says Olle Kampe, chair of the Nobel Committee. The Nobel panel added: "Their discoveries have laid the foundation for a new field of research and spurred the development of new treatments, for example for cancer and autoimmune diseases.""
The Nobel Prize in Physiology or Medicine 2025 recognizes discoveries explaining how the immune system attacks infections while sparing the body's own cells. Shimon Sakaguchi, Mary Brunkow and Fred Ramsdell discovered regulatory immune cells described as 'security guards' that remove immune cells capable of attacking the body. Their work is guiding development of new treatments for autoimmune diseases and cancer. The winners share a prize fund of 11 million Swedish kronor (about 870,000). Olle Kampe, chair of the Nobel Committee, said the discoveries were decisive for understanding immune function and established a foundation for new research and therapies.
Read at www.bbc.com
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