#mitochondrial-dysfunction

#mitochondrial-dysfunction

As we age, many of us experience subtle changes in our mental clarity-we can't remember a name, we experience difficulty multitasking, or we forget where we left our keys. For decades, scientists have believed that cognitive decline was an inevitable part of growing older, a process termed " age-related memory impairment." But what if this cognitive decline is preventable, or even reversible?

"B-cells, which are responsible for producing antibodies, rely on BCRs for survival and growth. While most research has focused on the IgM variant of BCRs, this study sheds light on the lesser-understood IgG1 variant," said Vipul Shukla, PhD, assistant professor of Cell and Developmental Biology, who was co-senior author of the study. "Our lab focuses on understanding the molecular control of B-cell function, which are a key component of the immune system responsible for generating antibodies,"