#glynac

#glynac

The thymus is a specialized immune organ responsible for maturing T cells, thereby producing a diverse T cell repertoire crucial for mounting an adaptive immune response. The thymus itself decays with age and eventually transforms entirely into adipose tissue through a process known as thymic involution.

Researchers administered one of four doses of stem cells to 118 people between 70 and 85 years old, all of whom had frailty. In a timed walking test nine months after treatment, those who had received the highest dose could walk about 60 metres farther, on average, than they could before treatment.

We've always said that SuperAgers show that the aging brain can be biologically active, adaptable, flexible, but we didn't know why. This is biological proof that their brains are more plastic, and a real discovery that shows that neurogenesis of young neurons in the hippocampus may be a contributing factor.

There is a lot of interest today in identifying ways to not just live longer, but to live better. It was exciting to see the benefits of a multivitamin linked with markers of biological aging. This study opens the door to learning more about accessible, safe interventions that contribute to healthier, higher-quality aging.

"As we get older, the immune system is shifting away from good inflammation," which is the body's short-term, acute response to fend off injury or infection and promote healing, explains Dr. Thomas Marron, one of the researchers leading the new study. Marron directs early phase clinical trials at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

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