So if you may remember, years ago now, I started talking about building my own not-for-profit healthcare service for trans adults and trans youth,
Researchers have developed a skin-permeable polymer that can deliver insulin into the body, which they say could one day offer an alternative to injections for diabetes management. The skin's structure presents a formidable barrier to the delivery of large drugs but in this work a team show that their polymer can penetrate though the different layers without causing damage. Insulin attached to this polymer was able to reduce blood glucose levels in animal models for diabetes at a comparable speed to injected insulin.
Therapeutic genome-editing efforts, including more than 70 clinical trials so far, have predominantly used programmable nucleases, base editors or prime editors to disrupt or correct disease-associated genes in an allele-specific manner. These approaches have proven to be effective in patients or in animal models for the treatment of disorders such as sickle-cell disease6,7, T cell leukaemia8, hypercholesterolaemia9,10, alpha-1-antitrypsin deficiency10, chronic granulomatous disease11, progeria12, spinal muscular atrophy13, prion disease14, alternating hemiplaegia of childhood15 and many other genetic diseases. Although allele-specific therapeutic genome-editing strategies offer treatments for many serious diseases with few treatment options, the breadth of the global genetic disease crisis,
The findings supplement previous results from the PARTNER 3 trial, which found that patients who underwent a transcatheter aortic valve replacement, or TAVR - a minimally invasive procedure in which the narrowed aortic valve is replaced via percutaneous access with wires and catheters through the femoral artery - demonstrated similar five-year survival rates to patients who underwent traditional aortic-valve replacement surgery.
In the US alone, 12% of the population have reported using injectable weight loss drugs, such as Wegovy/Ozempic, Zepbound and Saxenda, over the past year. That's more than double the number recorded in early 2024. In European countries, demand is also on the rise: In the UK, for example, a survey found that 21% of the public had accessed an online or in-person pharmacy in the past year to obtain weight loss medication.
Picture a plastic surgeon's office. You might imagine a sleek Los Angeles practice, with discreet entrances meant to conceal celebrities from the paparazzi. Maybe a Dallas high-rise, where monied housewives spend on postpartum mommy makeovers. Or a Miami location, where influencers and OnlyFans stars film TikToks of their BBLs. One city you might not think of is Washington DC. But its buttoned-up reputation belies a newly buzzing industry.
My family has an interesting dynamic when it comes to medical decisions. While my older sister is a trained doctor in western allopathic medicine, my parents are big believers in traditional remedies. Having grown up in a small town in India, I am accustomed to rituals. My dad had a ritual, too. Every time we visited his home village in southern Tamil Nadu, he'd get a bottle of thick, pungent, herb-infused oil from a vaithiyar, a traditional doctor practising Siddha medicine.
Kidney stones can often leave you feeling unsettled and in fear they might return, even when you're recovering after the ESWL procedure. Therefore, you might wonder which daily habits truly make a difference and which ones may detract from your recovery. You might also want reassurance that the changes you make are safe, manageable and genuinely supportive of your recovery. Continue reading to understand the daily choices that may help you lower your risk of developing stones again.
Every great career begins with a foundation built on service, discipline, and heart - and for Darrel Kalinski, those values have guided every chapter of his life. From the athletic fields of his youth to the operating rooms of major hospitals, his story is one of dedication, resilience, and a steady pursuit of excellence. "I've always believed that if you're going to do something, you do it with integrity and purpose," Kalinski says. "That principle has carried me through every stage of my life - from the Navy to healthcare to fatherhood."
Severe dental disease is common among people addicted to methamphetamine and cocaine, as is tooth loss, complicating treatment and recovery. Oral health is often entirely overlooked by individuals addicted to drugs. Yet many illicit drugs directly alter the balance of hormones and neurotransmitters regulating salivary flow, leading to dry mouth, cavities, and oral infections. Most people admitted to treatment programs for substance use disorders (SUDs) haven't seen a dentist for years-and still won't see one.
Chuck was just as cool a guy as you could ask for. I ran into him at the gas station by my house one night. It was a complete surprise as his shop was on the other side of town, but we struck up a convo and had a laugh. We said good night like nothing was out of the ordinary.
A hard smart under hot wash of coffee. Beneath the pulped swell of winter citrus or a sharp draw of winter air. Not delicately, Dr. Wayne tested each molar etched through. In sleep I will fit one to another and scrape. What gnaws at me: my own mouth, now hindered and harbored by this night guard. In the day, set aside, its plastic holds a phantom jaw.
From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging. At such a critical moment in US history, we need reporters on the ground.
After months of investigation, a team of scientists at the University of Virginia School of Medicine determined the 47-year-old airline pilot died from alpha-gal syndrome, an allergy to red meat and other products from mammals that can unknowingly develop after a tick bite. According to researchers, the man, who has not been identified, had two extreme reactions to eating beef in the summer of 2024, after he'd been bitten multiple times by lone star ticks.
While we all forget a word now and then, if this becomes a pattern, it could signal a problem. "Difficulty with language including word-finding difficulty, incorrect sentence construction, or difficulty with self-expression can present well before the loss of memory," said Dr. Arif Dalvi, a neurologist and physician chief of the Movement Disorders Program at Delray Medical Center. "Visual or spatial skills can also be affected early," Dalvi continued. "A common way this presents is difficulty navigating a previously familiar route or needing GPS directions to a route that was previously known."
The latest thermometers are ditching mercury and replacing it with high-tech sensors instead. One smart thermometer, developed by French health technology company Withings, received FDA clearance on Thursday. The Withings BeamO "thermometer of the future" not only takes a person's temperature. It can also perform a medically certified electrocardiogram and an auscultation for monitoring heart and lung health in less than a minute.
Your brain is an incredible network of over 160 billion cells linked by over 100 trillion connections. Each day and each moment, it's being influenced by the choices you make. While no single signal or chemical determines your brain's fate, incredible scientific research over the last few decades have revealed that a certain molecule produced by your body's cells may be uniquely capable of growing your brain and even growing new brain cells.
Her journey began not in a lab, but in her own life. After years of doing "everything right" and still struggling with her weight, Dr. Pobee turned to genetic testing to uncover the truth behind her body's resistance. What she discovered changed everything - her unique biology held the key. By learning how her genes influenced her metabolism, she lost 100 pounds and kept it off.
Brinlee Luster brushed off the exhaustion and stomach cramps as stress. She was finishing college, planning a wedding, and racing toward graduation. At first, the changes were easy to dismiss. A cold that wouldn't clear up. An unsettled, uncomfortable feeling in her gut that could be anxiety. Feeling winded on an easy hike. But as the pain sharpened and she started leaving class 10 times to use the bathroom, she knew something was seriously wrong.
The ketogenic diet (KD) is unique in improving symptoms for many conditions, from epilepsy to addiction, according to a recent JAMA Psychiatry article. It's a high-fat, very-low-carbohydrate nutritional therapy that shifts the body's from glucose dependence to ketone production as the primary fuel source. Increasing evidence implicates metabolic dysfunction, neuroinflammation, and neurotransmitter imbalance in psychiatric and addictive disorders-domains directly influenced by ketosis.
Now that it's successfully completed a pilot period, the company is bringing a 30-minute, lab-accurate PCR test for three common sexually transmitted infections to women at home. From a self-collected vaginal swab, the $149.99 test can diagnose chlamydia, gonorrhea, and trichomoniasis-three common infections that can all easily be treated with antibiotics. It also connects patients who test positive with a healthcare provider via United Healthcare's OptumNow telehealth service.
