The findings supplement previous results from the PARTNER 3 trial, which found that patients who underwent a transcatheter aortic valve replacement, or TAVR - a minimally invasive procedure in which the narrowed aortic valve is replaced via percutaneous access with wires and catheters through the femoral artery - demonstrated similar five-year survival rates to patients who underwent traditional aortic-valve replacement surgery.
In the US alone, 12% of the population have reported using injectable weight loss drugs, such as Wegovy/Ozempic, Zepbound and Saxenda, over the past year. That's more than double the number recorded in early 2024. In European countries, demand is also on the rise: In the UK, for example, a survey found that 21% of the public had accessed an online or in-person pharmacy in the past year to obtain weight loss medication.
My family has an interesting dynamic when it comes to medical decisions. While my older sister is a trained doctor in western allopathic medicine, my parents are big believers in traditional remedies. Having grown up in a small town in India, I am accustomed to rituals. My dad had a ritual, too. Every time we visited his home village in southern Tamil Nadu, he'd get a bottle of thick, pungent, herb-infused oil from a vaithiyar, a traditional doctor practising Siddha medicine.
Every great career begins with a foundation built on service, discipline, and heart - and for Darrel Kalinski, those values have guided every chapter of his life. From the athletic fields of his youth to the operating rooms of major hospitals, his story is one of dedication, resilience, and a steady pursuit of excellence. "I've always believed that if you're going to do something, you do it with integrity and purpose," Kalinski says. "That principle has carried me through every stage of my life - from the Navy to healthcare to fatherhood."
Severe dental disease is common among people addicted to methamphetamine and cocaine, as is tooth loss, complicating treatment and recovery. Oral health is often entirely overlooked by individuals addicted to drugs. Yet many illicit drugs directly alter the balance of hormones and neurotransmitters regulating salivary flow, leading to dry mouth, cavities, and oral infections. Most people admitted to treatment programs for substance use disorders (SUDs) haven't seen a dentist for years-and still won't see one.
Chuck was just as cool a guy as you could ask for. I ran into him at the gas station by my house one night. It was a complete surprise as his shop was on the other side of town, but we struck up a convo and had a laugh. We said good night like nothing was out of the ordinary.
A hard smart under hot wash of coffee. Beneath the pulped swell of winter citrus or a sharp draw of winter air. Not delicately, Dr. Wayne tested each molar etched through. In sleep I will fit one to another and scrape. What gnaws at me: my own mouth, now hindered and harbored by this night guard. In the day, set aside, its plastic holds a phantom jaw.
Everyone has heard of the weight loss drug Ozempic. Other brands include Weg­ovy, Mounjaro and Zepbound. These are all basically the same and are based on a natural hormone called GLP-1. Your body makes GLP-1 after a meal and it makes you feel full, stopping you eating.
After months of investigation, a team of scientists at the University of Virginia School of Medicine determined the 47-year-old airline pilot died from alpha-gal syndrome, an allergy to red meat and other products from mammals that can unknowingly develop after a tick bite. According to researchers, the man, who has not been identified, had two extreme reactions to eating beef in the summer of 2024, after he'd been bitten multiple times by lone star ticks.
While we all forget a word now and then, if this becomes a pattern, it could signal a problem. "Difficulty with language including word-finding difficulty, incorrect sentence construction, or difficulty with self-expression can present well before the loss of memory," said Dr. Arif Dalvi, a neurologist and physician chief of the Movement Disorders Program at Delray Medical Center. "Visual or spatial skills can also be affected early," Dalvi continued. "A common way this presents is difficulty navigating a previously familiar route or needing GPS directions to a route that was previously known."
The latest thermometers are ditching mercury and replacing it with high-tech sensors instead. One smart thermometer, developed by French health technology company Withings, received FDA clearance on Thursday. The Withings BeamO "thermometer of the future" not only takes a person's temperature. It can also perform a medically certified electrocardiogram and an auscultation for monitoring heart and lung health in less than a minute.
Your brain is an incredible network of over 160 billion cells linked by over 100 trillion connections. Each day and each moment, it's being influenced by the choices you make. While no single signal or chemical determines your brain's fate, incredible scientific research over the last few decades have revealed that a certain molecule produced by your body's cells may be uniquely capable of growing your brain and even growing new brain cells.
Her journey began not in a lab, but in her own life. After years of doing "everything right" and still struggling with her weight, Dr. Pobee turned to genetic testing to uncover the truth behind her body's resistance. What she discovered changed everything - her unique biology held the key. By learning how her genes influenced her metabolism, she lost 100 pounds and kept it off.
Brinlee Luster brushed off the exhaustion and stomach cramps as stress. She was finishing college, planning a wedding, and racing toward graduation. At first, the changes were easy to dismiss. A cold that wouldn't clear up. An unsettled, uncomfortable feeling in her gut that could be anxiety. Feeling winded on an easy hike. But as the pain sharpened and she started leaving class 10 times to use the bathroom, she knew something was seriously wrong.
The ketogenic diet (KD) is unique in improving symptoms for many conditions, from epilepsy to addiction, according to a recent JAMA Psychiatry article. It's a high-fat, very-low-carbohydrate nutritional therapy that shifts the body's from glucose dependence to ketone production as the primary fuel source. Increasing evidence implicates metabolic dysfunction, neuroinflammation, and neurotransmitter imbalance in psychiatric and addictive disorders-domains directly influenced by ketosis.
Now that it's successfully completed a pilot period, the company is bringing a 30-minute, lab-accurate PCR test for three common sexually transmitted infections to women at home. From a self-collected vaginal swab, the $149.99 test can diagnose chlamydia, gonorrhea, and trichomoniasis-three common infections that can all easily be treated with antibiotics. It also connects patients who test positive with a healthcare provider via United Healthcare's OptumNow telehealth service.
Pregnancy after loss is full of contradictions. It is hope that feels cautious, like it might dissolve if you breathe too hard. It is learning to live again inside a body that remembers grief. I am now officially in my third trimester, and each day brings small signs of life: a flutter, a roll, a hiccup, the steady rhythm of his heart.
The Jacksonville Jaguars made the move in Week 7 to run the offense through rookie two-way threat Travis Hunter -- and it brought out the best in him. He set season highs in catches (eight) and receiving yards (104) and caught his first touchdown pass while the rest of the offense was stagnant during a 35-7 loss to the Los Angeles Rams. After the Jaguars got back from their Week 8 bye, they planned to turn Hunter loose on offense again. But he suffered a non-contact LCL injury to his right knee during an Oct. 30 practice which derailed that idea.
Echocardiography is the most widely used cardiac imaging modality, capturing ultrasound video data to assess cardiac structure and function1. Artificial intelligence (AI) in echocardiography has the potential to streamline manual tasks and improve reproducibility and precision2. However, most echocardiography AI models are single-view, single-task systems that do not synthesize complementary information from multiple views captured during a full exam3,4, and thus lead to limited performance and scope of applications.
On Monday, the FDA announced that hormone replacement therapy (HRT) products will no longer carry black box warnings stating they cause increased risk of breast cancer, heart attack, and stroke. The label was added to these products in the early 2000s following the publication of the Women's Health Initiative study, the results of which experts say were misinterpreted. The FDA's announcement states that the study "found a statistically nonsignificant increase in the risk of breast cancer diagnosis.
First of all, congratulations! And don't worry. It's normal to want to see a doctor right away when you see those two side-by-side lines on a positive pregnancy test. But it's also pretty typical to have trouble getting an appointment to confirm you're pregnant. A physician friend of mine also recently went through this. Even with insider connections at her hospital, she couldn't see a doctor for another month.
At a certain point, older folks occasionally develop a penchant for making verbal slurs, mental stumbles, rambling speeches, and confusing responses. They often claim that they have no memory of making those misstatements; they might not be lying. They may be experiencing the most common consequences of advanced age coupled with chronic obesity due to a poor diet. Mind-wandering, confusion, and a reduced ability to organize and focus thoughts are classic early symptoms of dementia.
A nurse has admitted to professional misconduct over taking a photo of a surgical team carrying out an organ retrieval procedure in an operating theatre and later posting it on social media. A fitness-to-practise inquiry of the Nursing and Midwifery Board of Ireland heard there was no clinical justification for the nurse to take the photograph on May 22, 2023, and to subsequently post it on her Facebook and Instagram accounts.
Metformin-associated lactic acidosis (MALA) is an uncommon but potentially life-threatening complication linked to the diabetes medication metformin. The condition occurs when excessive lactic acid builds up in the body, leading to dangerous changes in blood chemistry. Researchers developed and evaluated a clinical protocol aimed at improving how MALA is recognized and treated. Their findings were presented at ASN Kidney Week 2025.