Men in Tanzania switched from an African diet to a Western one - here's what happened to their bodies
Dietary changes can cause rapid and significant health effects, especially when switching from a traditional to a Western diet.
Short-term exposure to a Western diet leads to weight gain and increased inflammatory markers, with some effects persisting after returning to traditional eating.
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan - Nature
The signalling pathways ERK, STK11, AMPK, mTORC1, and IGF1-insulin regulate lifespan and are perturbed in aging organisms, highlighting the importance of AMPK-mTORC1 axis for metabolic health.