#mc4r

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Science
fromNature
4 days ago

Daily briefing: Gene that causes obesity also shields against heart disease

Rare MC4R gene variants associate with obesity yet correspond to lower LDL cholesterol and reduced heart disease rates.
fromInsideHook
3 days ago

A Gene That Causes Obesity Can Also Help With Cholesterol

"BMI is just one data point, along with many others, that needs to be considered to determine a person's health," Yale's Wajahat Mehal, MD told Yale Medicine in 2023. The latest sign that someone's weight and height are not the only factors to ponder when it comes to your health comes from a paper published this week in Nature Medicine, which neatly illustrates the more paradoxical aspects of genetics and the human body.
Medicine
Medicine
fromNature
5 days ago

This gene causes obesity - and shields against heart disease

Loss-of-function MC4R mutations cause severe obesity yet associate with lower LDL cholesterol levels and reduced rates of heart disease compared with BMI-matched peers.
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