"People with obesity due to relatively rare forms of a gene called MC4R have lower levels of 'bad' cholesterol and reduced rates of heart disease than do people with a similar body-mass index. The study emerged from an effort to understand the fundamental mechanisms that regulate body weight and why some people with obesity maintain good heart health. The results could point the way to better ways of staving off cardiovascular disease, suggest researchers."
"Success rates for Europe's leading research grants are declining - some to single percentage points - as a surge in applications far outweighs the funds available. Data gathered by Nature show that researchers, especially those at the start of their academic journeys, are facing increasingly fierce competition to pursue research careers. "We're extremely pleased that there is such a high demand for ERC grants. It shows that people have ideas for fundamental science, for frontier science, that there's a need for it,"
People with obesity caused by rare forms of the MC4R gene have lower levels of 'bad' cholesterol and reduced rates of heart disease than people with similar body-mass index. The finding stems from efforts to understand mechanisms regulating body weight and why some people with obesity maintain good heart health and could guide new ways to prevent cardiovascular disease. Success rates for Europe's leading research grants are declining, with some falling to single-percentage points as applications surge while funds remain limited, intensifying competition. Researchers have engineered over two dozen fluorescent proteins that vary by colour and fluorescence lifetime, enabling time-resolved imaging.
Read at Nature
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