#homologous-recombination

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#longevity #dna-repair #cgas #naked-mole-rat
OMG science
fromenglish.elpais.com
3 days ago

Chinese scientists discover the DNA secret behind the naked mole-rat's astonishing longevity

Four mutations enhance naked mole-rat DNA repair via altered cGAS regulation of homologous recombination, supporting exceptional, healthy longevity.
Science
fromNature
4 days ago

Naked mole rats live for decades - genetic tweaks reveal insights into ageing

Four amino-acid substitutions in cGAS enable persistent enzyme activity that enhances DNA repair, supporting genomic maintenance and longevity in naked mole rats.
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