#base-editing

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fromNature
1 day ago

Personalized gene editing helped one baby: can it be rolled out widely?

The groundbreaking clinical trial, described on 31 October in the American Journal of Human Genetics, will deploy an offshoot of the CRISPR-Cas9 gene-editing technique called base editing, which allows scientists to make precise, single-letter changes to DNA sequences. The study is expected to begin next year, after its organizers spent months negotiating with US regulators over ways to simplify the convoluted path a gene-editing therapy normally has to take before it can enter trials.
Medicine
OMG science
fromHarvard Gazette
6 months ago

Rewriting genetic destiny - Harvard Gazette

David Liu's gene-editing technology, base editing, offers hope for patients with genetic diseases by providing safer and effective treatment options.
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