A recent study by Rutgers University-New Brunswick highlights that exercise activates specialized brain cells associated with insulin response, potentially improving cognitive function. Published in Aging Cell, it emphasizes the significance of targeting insulin action through new therapies to combat or prevent dementia. The study explored neuronal extracellular vesicles, which transport vital molecules like proteins affecting insulin sensitivity. Improved insulin sensitivity leads to better glucose usage, particularly in muscles, contrasting with insulin resistance commonly seen in diabetes, which detrimentally affects cognitive abilities.
We believe this work is important because it suggests exercise may work to improve cognition and memory by improving the abilities of insulin to act on the brain.
Extracellular vesicles, once dismissed by researchers as 'cell dust,' have in the past 15 years grown exponentially in recognition as important players in the microscopic world of the human body.
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