The importance of memory to our identity highlights a core aspect of neuroscience: how the brain encodes and retains memories is vital for learning.
Long-term potentiation (LTP) is a crucial discovery in neuroscience, showing that stimulating synaptic connections strengthens signal transmission and is believed to underlie memory formation.
PKMzeta emerged as a key player in the memory process after experiments indicated that blocking it could erase established memories in rats, suggesting its essential role.
However, the fleeting nature of PKMzeta, which lasts only hours to days, raises the question of how such a short-lived molecule can support long-term memory retention.
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