Patients who undergo GLP-1 pharmacotherapy need strategies to prevent weight regain after treatment stops. Evidence from 32 studies shows that exercise leads to only a modest average weight loss of about 2 kg. Caloric restriction stands out as the only proven effective method for weight loss. Despite the health benefits of exercise for cardiovascular and bone health, its role in significant weight loss is limited. Understanding the nuances of energy expenditure is critical in setting realistic weight management goals for patients.
The impact of exercise on weight loss is modest, with a modest average loss of weight of only about 2 kg from regular exercise compared to controls.
Caloric restriction is the only scientifically proven dietary intervention that achieves significant weight loss, while exercise is less effective.
Patients need guidance on maintaining weight loss after GLP-1 therapy, with a focus on emphasizing caloric restriction over exercise for effectiveness.
Energy expenditure is not linear; increased activity does not necessarily equate to greater calorie burn or weight loss.
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