Researchers from Northwestern Medicine found that disturbances in circadian rhythms, especially in muscle tissue, when paired with unhealthy diets, can significantly increase the risk of developing diabetes. The study specifically examined a mouse model lacking the BMAL1 gene responsible for regulating circadian rhythms and muscle metabolism. This research highlights the importance of muscle clocks in energy metabolism and reveals that circadian disruption can result in accelerated glucose intolerance, even when weight gain is not observed, outlining critical links between our internal biological clocks and metabolic health.
When we mess up our circadian rhythms through environmental circadian disruption like shift work, jet lag or sleep deprivation, it's possible that it's impacting our muscle clocks and metabolism.
The body's natural circadian clock is comprised of proteins called transcription factors that are present throughout the body including muscle tissue.
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