Medicine
fromScienceDaily
1 week agoThe body trait that helps keep your brain young
Higher muscle mass and lower visceral abdominal fat associate with a younger biological brain age and reduced risk of future brain disease.
A large study led by scientists at McMaster University has found that fat stored deep inside the abdomen and liver can quietly injure arteries, even in people who seem healthy on the outside. The research, published on October 17, 2025, in Communications Medicine, questions the long-standing use of body-mass index (BMI) as a reliable indicator of obesity and heart risk. It offers new evidence that the fat people cannot see may be just as dangerous as the weight they can.
Being overweight has long been linked to heart conditions and type 2 diabetes, but even people who look thinner could be at risk, researchers suggest. A new study led by researchers at McMaster University in Ontario, Canada, explains there is such a thing as being skinny-fat - someone who appears to be healthy and slim but in fact has hidden fat deep inside their organs.
When injuries or infections occur, the immune system mounts a protective response by releasing cells and proteins to affected tissues. This complex cascade is called inflammation. But as we age, inflammation gradually increases and becomes persistent instead of being a state that occurs only when things go wrong. Among the cells that that help to regulate this inflammageing are a variety of macrophages - white blood cells that hoover up pathogens and cellular debris - that reside in fat tissue.