#synthetic-chemistry
#synthetic-chemistry
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#biocatalysis #chemical-research #catalysis #heterocycles #carbonyl-replacement #bioactive-molecules
fromwww.nature.com
1 month agoDirect conversion from alkenes to alkynes
Alkynes are widely used as feedstock chemicals and functional groups in organic chemistry. However, while the hydrogenation from an alkyne to an alkene is well established, typical methods for the reverse reaction—conversion of an alkene to an alkyne—are based on elimination chemistry reported in the 1860s and use forcing conditions (strong base or high temperatures).
fromwww.nature.com
1 month agoScience
Alcohol group migration by proximity-enhanced H atom abstraction
A new photocatalytic editing method enables precise migration of alcohol functional groups to nearby molecular sites with predictable outcomes, streamlining molecular optimization and enabling access to challenging oxygenation patterns.
fromNature
9 months agoRedox-powered autonomous directional C-C bond rotation under enzyme control - Nature
This paper presents a molecular motor that exhibits autonomous unidirectional rotation about a C-C single bond, driven by a cyclic redox reaction network involving concurrent biocatalytic oxidation and chemical reduction.
Science
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