#immune-checkpoint-blockade

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Medicine
fromNature
2 days ago

Proteotoxic stress response drives T cell exhaustion and immune evasion - Nature

Proteomic profiling of exhausted T cells reveals pathway-specific transcript–protein discordance and identifies T cell–exhaustion-specific protein-level regulatory mechanisms.
Cancer
fromNature
2 months ago

Microbiota-driven antitumour immunity mediated by dendritic cell migration - Nature

Immune checkpoint blockade therapies significantly improve cancer survival but have low complete response rates, necessitating new biomarkers and strategies.
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