#cell-biology

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#human-cell-atlas

'Major milestone' as scientists map all human body cells - and the breakthrough will help target diseases

A comprehensive human cell map will enhance disease treatment and research, impacting conditions like cancer, diabetes, and arthritis.

What is a cell type, really? The quest to categorize life's myriad forms

Cellular individuality complicates research, as each cell exhibits unique characteristics which may influence drug resistance in cancer treatment.

'Major milestone' as scientists map all human body cells - and the breakthrough will help target diseases

A comprehensive human cell map will enhance disease treatment and research, impacting conditions like cancer, diabetes, and arthritis.

What is a cell type, really? The quest to categorize life's myriad forms

Cellular individuality complicates research, as each cell exhibits unique characteristics which may influence drug resistance in cancer treatment.
morehuman-cell-atlas

The Human Cell Atlas from a cell census to a unified foundation model

Cell atlases leverage AI and new methods to reveal critical biological insights and are transforming our understanding of biology and medicine.

Researchers Give Animal Cells the Ability to Photosynthesize for the First Time

A Japanese research team successfully transplanted active chloroplasts into animal cells, demonstrating functional photosynthesis and challenging previous assumptions about cell compatibility.
#alzheimers-disease

Alzheimer's timeline shows changes start as trickle, become torrent

Alzheimer's disease has two distinct phases, indicating a slow onset followed by rapid deterioration, with vulnerable neurons identified for potential early treatment.

Alzheimer's timeline shows changes start as trickle, become torrent

Alzheimer's disease has two phases, with somatostatin neurons being particularly vulnerable in the early phase.

Alzheimer's timeline shows changes start as trickle, become torrent

Alzheimer's disease has two distinct phases, indicating a slow onset followed by rapid deterioration, with vulnerable neurons identified for potential early treatment.

Alzheimer's timeline shows changes start as trickle, become torrent

Alzheimer's disease has two phases, with somatostatin neurons being particularly vulnerable in the early phase.
morealzheimers-disease
#dna

Researchers create first map of the spliceosome, an Achilles heel of cancer

Cells utilize the same DNA across types, but spliceosome machinery specifies which genes are expressed, creating diverse cell functions.

The fusion of two sisters into a single woman suggests that human identity is not in our DNA

The case of Karen Keegan, a chimeric woman, challenges the perception of DNA defining individual identity.

Researchers create first map of the spliceosome, an Achilles heel of cancer

Cells utilize the same DNA across types, but spliceosome machinery specifies which genes are expressed, creating diverse cell functions.

The fusion of two sisters into a single woman suggests that human identity is not in our DNA

The case of Karen Keegan, a chimeric woman, challenges the perception of DNA defining individual identity.
moredna
#health

Scientists Studying Aging Are Finally Zeroing In On What Actually Triggers Age-Related Diseases

Aging is a natural process linked to metabolic decline and increased disease risk, emphasizing the need for a deeper understanding of their connection.

Daily briefing: Variant of mpox virus is getting better at human-to-human transmission

Semaglutide significantly alleviates obesity-related knee arthritis pain, matching the efficacy of painkillers.
Advanced mapping of tumor cells offers crucial insights for cancer treatment development.
New findings on protocell structures may shed light on the evolution of cell membranes.

Scientists Studying Aging Are Finally Zeroing In On What Actually Triggers Age-Related Diseases

Aging is a natural process linked to metabolic decline and increased disease risk, emphasizing the need for a deeper understanding of their connection.

Daily briefing: Variant of mpox virus is getting better at human-to-human transmission

Semaglutide significantly alleviates obesity-related knee arthritis pain, matching the efficacy of painkillers.
Advanced mapping of tumor cells offers crucial insights for cancer treatment development.
New findings on protocell structures may shed light on the evolution of cell membranes.
morehealth
#scientific-research

Rain may have helped form the first cells, kick-starting life as we know it

Rainwater played a crucial role in stabilizing early cells, facilitating the evolution of complex life.

Author Correction: UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis - Nature

Collaborative research in cell biology can lead to significant advancements.
Integrating expertise from multiple institutions enhances scientific inquiry and innovation.

Rain may have helped form the first cells, kick-starting life as we know it

Rainwater played a crucial role in stabilizing early cells, facilitating the evolution of complex life.

Author Correction: UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis - Nature

Collaborative research in cell biology can lead to significant advancements.
Integrating expertise from multiple institutions enhances scientific inquiry and innovation.
morescientific-research
#protein-interactions

Red light, green light: flickering fluorophores reveal biochemistry in cells

Understanding protein interactions in live cells is revolutionizing our knowledge of cellular behavior.
The PAPA-fSMT method allows detailed study of protein complex dynamics during gene transcription.

'Phenomenal' tool sequences DNA and tracks proteins - without cracking cells open

The new microscopy technique enables imaging of proteins and DNA interactions within intact cells, advancing our understanding of cellular processes.

Red light, green light: flickering fluorophores reveal biochemistry in cells

Understanding protein interactions in live cells is revolutionizing our knowledge of cellular behavior.
The PAPA-fSMT method allows detailed study of protein complex dynamics during gene transcription.

'Phenomenal' tool sequences DNA and tracks proteins - without cracking cells open

The new microscopy technique enables imaging of proteins and DNA interactions within intact cells, advancing our understanding of cellular processes.
moreprotein-interactions
#gene-regulation

Mystery Droplets Inside Cells May Play Vital Roles in Life

Biomolecular condensates challenge traditional views of cell organelles, suggesting they play crucial roles in cell function and disease.

Two U.S. scientists win Nobel Prize in Physiology, Medicine

Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize for their discovery of microRNA and its role in gene regulation.
Their work is fundamental for understanding cell development and potential future applications.

Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease - Nature

Non-coding RNAs are essential for gene regulation and maintaining cellular functions.

Mystery Droplets Inside Cells May Play Vital Roles in Life

Biomolecular condensates challenge traditional views of cell organelles, suggesting they play crucial roles in cell function and disease.

Two U.S. scientists win Nobel Prize in Physiology, Medicine

Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize for their discovery of microRNA and its role in gene regulation.
Their work is fundamental for understanding cell development and potential future applications.

Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease - Nature

Non-coding RNAs are essential for gene regulation and maintaining cellular functions.
moregene-regulation

Your cells are dying. All the time.

Understanding the various modes of cell death can lead to improved treatments for diseases such as cancer and infections.

Cracking the tubulin code: enzyme structures offer clues to microtubule control

Microtubules' functionality is governed by a 'tubulin code' formed through specific modifications.
#cancer-research

Goyal and Kennedy Named 2024 Pew Scholars - News Center

Feinberg faculty members named 2024 Pew Scholars, accelerating biomedical sciences.

Author Correction: Life-cycle-coupled evolution of mitosis in close relatives of animals - Nature

Collaboration among international researchers is crucial for addressing complex scientific challenges in cell biology and cancer research.

Goyal and Kennedy Named 2024 Pew Scholars - News Center

Feinberg faculty members named 2024 Pew Scholars, accelerating biomedical sciences.

Author Correction: Life-cycle-coupled evolution of mitosis in close relatives of animals - Nature

Collaboration among international researchers is crucial for addressing complex scientific challenges in cell biology and cancer research.
morecancer-research

How Did the First Cells Arise? With a Little Rain, Study Finds.

Rain may have been crucial to the emergence of life, influencing the formation of protocells that led to early cellular evolution.

Leonard Hayflick, Who Discovered Why No One Lives Forever, Dies at 98

Leonard Hayflick discovered that human cells can only divide a limited number of times, setting a natural cap on human lifespan.

Evolution of a novel adrenal cell type that promotes parental care - Nature

The emergence of a novel cell type in the adrenal gland of oldfield mice contributes to the evolution of monogamous-typical parental behaviors.

Bridging structural and cell biology with cryo-electron microscopy - Nature

Cryo-EM has revolutionized the study of large, functional complexes in structural biology.
The interplay between cryo-EM and cryo-electron tomography shows promise in visualizing macromolecules in their natural context.
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