Aging may not be uniform, as biological age can differ significantly from chronological age, impacting health predictions. Research by Dr. Steve Horvath emphasizes biological age's relevance in morbidity risk assessment over chronological age. A recent Nature Aging study explores the relationships among genetic mutations, methylation, and aging, revealing a link between somatic mutation and epigenetic changes. The study opens new avenues for understanding aging mechanisms, suggesting mutations can influence methylation patterns. Future research may clarify whether mutations or methylation processes drive biological aging, contributing to innovative strategies for aging prevention and reversal.
In 2022, aging researcher Dr. Steve Horvath told The Guardian that "biological age is a better predictor of morbidity risk than chronological age."
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