Science seeks keys to human longevity in the genetic mixing of Brazilian supercentenarians
Briefly

Science seeks keys to human longevity in the genetic mixing of Brazilian supercentenarians
"Life expectancy in the countries with the greatest longevity, such as Japan, Italy, and Spain, hovers around 84 years. But some people live for another 30 years or so. Spaniard Maria Branyas, for example, lived past 117. These are the supercentenarians. And not only do they live longer, but, as was the case with the Catalan woman, they rarely reach the end suffering from cardiorespiratory problems, Alzheimer's, or cancer, just with the ailments typical of such advanced age."
"Brazil is a less developed country with limited access to modern medicine for a large part of its population and a high degree of genetic mixing. And surprisingly, it has a large number of centenarians and a significant number of supercentenarians. Researchers at the Human Genome and Stem Cell Research Center at the University of Sao Paulo have compiled the largest sample of centenarians (160 and counting), including some 20 supercentenarians aged over 110."
Life expectancy in long-lived countries such as Japan, Italy, and Spain is around 84 years, while some people live roughly 30 years longer and become supercentenarians. Supercentenarians often avoid terminal cardiorespiratory disease, Alzheimer's, or cancer and instead experience ailments typical of very advanced age. Brazil, despite limited access to modern medicine for many and high genetic admixture, has a large number of centenarians and significant supercentenarian representation. The Human Genome and Stem Cell Research Center at the University of Sao Paulo assembled over 160 centenarians, including about 20 aged over 110, and collected genetic, epigenetic, molecular, cellular, ancestry, behavioral, and living-conditions data. The cohort continues to expand.
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