We know that when we shut off the checkpoints that control that reward circuit, we start to see reinforcing behavior like addiction," explains Jay McLaughlin, a professor of pharmacodynamics at the University of Florida and a coauthor on the new study.
"Opioid addicts who are experiencing overdose will report to the emergency room breathing once or twice a minute," McLaughlin says. This hypoxia-or lack of oxygen-is what kills people.
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