Sean Payton's return to New Orleans was marred by a 33-10 loss, marking the Broncos' fourth win in five games while the Saints fell to 2-5.
Doug Pederson's Jacksonville Jaguars face a must-win game against the struggling Patriots as they attempt to salvage their season after a dismal 1-5 start.
Quarterback Trevor Lawrence's performance has disappointed, averaging 222.3 yards per game and the Jaguars' defense remains among the worst in the league.
With a crucial matchup against New England looming, the Jaguars' playoff hopes hinge on a turnaround performance; failure could lead to major coaching changes.
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