Head coach Kyle Shanahan expressed optimism over running back Isaac Guerendo's return, noting that even a limited practice is a positive sign as the team prepares for their matchup against the Lions.
Nick Bosa is trending positively as a full participant, indicating his capability to contribute effectively in upcoming games despite previously dealing with hip and oblique injuries.
Coach Shanahan confirmed that several players, including Aaron Banks and Dre Greenlaw, are sidelined for the season, complicating the team's depth as they approach crucial games.
With only two healthy starting offensive linemen expected for Sunday, the 49ers face significant challenges if players like Colton McKivitz don’t recover in time.
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