Christian McCaffrey's injury troubles are worsening, leading the 49ers to consider placing him on injured reserve, which could sideline him for the next four games.
Coach Kyle Shanahan indicated the severity of McCaffrey's right Achilles tendinitis and calf strain has increased, which is concerning for his availability moving forward.
Jordan Mason is set for his second straight start after an impressive performance against the Jets, reflecting the depth and resilience of the 49ers' running game.
The 49ers are managing multiple injuries effectively, with key players like Talanoa Hufanga and Dee Winters listed as doubtful or questionable, demonstrating their need for depth.
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