The 49ers are facing significant offensive challenges with injuries to key players like George Kittle and Deebo Samuel, impacting their game strategy.
Despite offensive setbacks, the 49ers' defense stands strong with all starters available, including key players like Nick Bosa and Talanoa Hufanga.
The 49ers have elevated Brayden Willis and Sam Okuayinonu from the practice squad to bolster their lineup in the absence of injured starters.
With a unique situation, the 49ers maintain four quarterbacks under contract, showcasing depth and strategic planning amidst ongoing injuries to the roster.
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