Researchers have created a four-dimensional cell atlas of spinal-cord injury in mice, detailing cell responses to varying severities of injury, facilitating the development of tailored therapies.
The atlas, built using machine-learning algorithms and RNA sequencing data, provides a valuable resource for studying spinal-cord injury and offers insights for developing new treatments.
The study involved analyzing how nearly half a million cells responded to different types and severities of spinal cord injury over time using RNA-sequencing tools.
The spinal cord's isolated nature from the immune system changes when injuries occur, leading to immune cell infiltration and activation at the injury site.
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