Researchers scanned genomes and discovered over 38,000 likely precursors and nearly 50,000 mature microRNAs across various species, demonstrating their evolutionary significance.
MicroRNAs regulate multiple genes, and their complexity can mask the effects of mutations, causing challenges in deciphering their precise roles and importance in development.
Loss of Dicer, essential for microRNA maturation, leads to severe developmental defects, underscoring the fundamental role of microRNAs in cellular and organismal survival.
The recognition of microRNA's importance through Nobel Prize illustrates the complexity of life at the cellular level and emphasizes the intricate regulatory networks necessary for survival.
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