As COVID-19 emerged, the world faced an unprecedented situation, which allowed researchers to study immune responses to the SARS-CoV-2 virus. Years later, scientists have learned that T cells, initially sidelined in favor of studying antibodies, are essential for immunity against the virus. While antibodies decline over time after vaccination, T cell responses remain robust and effective against variants of the virus. This new understanding emphasizes the need for a broader perspective on immune responses beyond just antibody levels in vaccine research.
Years later, scientists are still sifting through the data to garner a better understanding of how the immune system works.
As the pandemic went on, however, it became clear that T cells were a crucial arm of the immune response to SARS-CoV-2 and to COVID-19 vaccines.
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