Engineered cells take drugs deep into the brain and nowhere else
Engineered T cells can deliver drugs directly to brain tumors by crossing the blood-brain barrier.
The cells that help the immune system fight lung cancer
Specialized cells near tumors enhance T cell efficacy against lung cancer, creating a supportive microenvironment.
Author Correction: Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy
Correction does not affect interpretation of the data on T cell infiltration in tauopathy.
Uncovering Regulatory Mechanisms of T-cells in Chronic Inflammation - News Center
Lag3 expression in regulatory T-cells is critical for preventing autoimmune inflammation and may be a target for therapies in inflammatory conditions and cancer.
How a potent immune therapy loses its punch against a blood cancer
Therapeutic T cells used for AML may impair their own effectiveness through secreted proteins.
Fate induction in CD8 CAR T cells through asymmetric cell division - Nature
Asymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
New Cancer Vaccines Could Treat Some Types of Pancreatic, Colorectal and Other Deadly Forms of the Disease
A new experimental therapeutic vaccine shows promise for people with KRAS-mutated pancreatic or colorectal cancer.
The vaccine delivers tumor-targeting molecules directly into the lymph nodes, activating T cells and showing positive results in a phase 1 trial.
Inside the Quest to Reprogram Immune Cells Into An Anti-Aging Remedy
Senescent cells are damaged cells that accumulate in the body and contribute to age-related diseases.
Researchers have genetically engineered T cells to target and eliminate senescent cells, resulting in rejuvenation in aged mice and slower aging in young mice.
How a potent immune therapy loses its punch against a blood cancer
Therapeutic T cells used for AML may impair their own effectiveness through secreted proteins.
Fate induction in CD8 CAR T cells through asymmetric cell division - Nature
Asymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
New Cancer Vaccines Could Treat Some Types of Pancreatic, Colorectal and Other Deadly Forms of the Disease
A new experimental therapeutic vaccine shows promise for people with KRAS-mutated pancreatic or colorectal cancer.
The vaccine delivers tumor-targeting molecules directly into the lymph nodes, activating T cells and showing positive results in a phase 1 trial.
Inside the Quest to Reprogram Immune Cells Into An Anti-Aging Remedy
Senescent cells are damaged cells that accumulate in the body and contribute to age-related diseases.
Researchers have genetically engineered T cells to target and eliminate senescent cells, resulting in rejuvenation in aged mice and slower aging in young mice.