RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - NatureVaccine-induced T cells correlate with significantly improved recurrence-free survival in PDAC patients at extended follow-up.
How a potent immune therapy loses its punch against a blood cancerTherapeutic T cells used for AML may impair their own effectiveness through secreted proteins.
Fate induction in CD8 CAR T cells through asymmetric cell division - NatureAsymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - NatureVaccine-induced T cells correlate with significantly improved recurrence-free survival in PDAC patients at extended follow-up.
How a potent immune therapy loses its punch against a blood cancerTherapeutic T cells used for AML may impair their own effectiveness through secreted proteins.
Fate induction in CD8 CAR T cells through asymmetric cell division - NatureAsymmetric cell division in CARTs influences their functional divergence and has implications for improving CAR T-cell therapy efficacy.
Daily briefing: How a boy from the Bronx unearthed the workings of the UniverseThe effective strategies for scientific research include adopting open science policies and understanding immune responses, particularly in relation to COVID-19.
Four lessons COVID taught us about the immune systemT cells play a crucial role in the immune response to COVID-19 and should not be overlooked in vaccine studies.
Uncovering Regulatory Mechanisms of T-cells in Chronic Inflammation - News CenterLag3 expression in regulatory T-cells is critical for preventing autoimmune inflammation and may be a target for therapies in inflammatory conditions and cancer.
Precursors of exhausted T cells are preemptively formed in acute infectionT cell exhaustion can occur early in acute infections, not just in chronic conditions.
Four lessons COVID taught us about the immune systemT cells play a crucial role in the immune response to COVID-19 and should not be overlooked in vaccine studies.
Uncovering Regulatory Mechanisms of T-cells in Chronic Inflammation - News CenterLag3 expression in regulatory T-cells is critical for preventing autoimmune inflammation and may be a target for therapies in inflammatory conditions and cancer.
Precursors of exhausted T cells are preemptively formed in acute infectionT cell exhaustion can occur early in acute infections, not just in chronic conditions.
An early precursor CD8 T cell that adapts to acute or chronic viral infectionThe emergence of stem-like CD8+ T cells is crucial for effective immunity in chronic infections and cancer.
Engineered cells take drugs deep into the brain and nowhere elseEngineered T cells can deliver drugs directly to brain tumors by crossing the blood-brain barrier.
The cells that help the immune system fight lung cancerSpecialized cells near tumors enhance T cell efficacy against lung cancer, creating a supportive microenvironment.
Author Correction: Microglia-mediated T cell infiltration drives neurodegeneration in tauopathyCorrection does not affect interpretation of the data on T cell infiltration in tauopathy.