"Our study indicates one reason why maintaining body weight after initial weight loss is difficult. It means that one would have to 'fight' this memory to maintain body weight," said Ferdinand von Meyenn.
The study found that it wasn't the number of fat cells that change when a person gains weight, but rather how existing fat cells store nutrients.
These genetic changes lasted long after their weight-reduction surgery. This led the researchers to find that the molecular memory in fat cells was due to epigenetic changes to the genome.
Epigenetic changes occur when gene expression is altered by our environment meaning that rapid weight gain isn't necessarily inherited but can also be a result of events we experience in life.
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