The London Fire Brigade reported about 60 firefighters are tackling a blaze at the Royal Free Hospital, with eight fire engines deployed in response.
The cause of the fire remains unknown, but traffic in the area is expected to be heavily impacted as firefighting efforts continue.
London Ambulance Service responded to the fire, sending resources including ambulance crews and an incident response officer, with their crews arriving within six minutes.
Crews from surrounding fire stations, including Kentish Town and West Hampstead, remain on scene battling the fire, which was first reported at 11:15 GMT.
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