#vaccine-design

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fromNews Center
6 days ago

Mechanisms of Antibody Production May Help Improve Vaccines - News Center

Scientists led by Stephanie Eisenbarth, MD, PhD, the Roy and Elaine Patterson Professor of Medicine and director of the Center for Human Immunobiology, have discovered how critical IgA antibodies are produced through unexpected cellular pathways, findings that may help inform the design of more effective vaccines to prevent infections, according to a recent study published in Immunity. Immunoglobulin (Ig)A is an antibody that serves as the first line of defense for mucosal tissues that comprise the inner lining of organs in the respiratory system and digestive
Science
fromwww.nature.com
3 weeks ago
Science

Potent neutralization of Marburg virus by a vaccine-elicited antibody

Engineered prefusion MARV glycoprotein improves expression, stability, and immunogenicity, and monoclonal antibody MARV16 broadly neutralizes and therapeutically protects against Marburg viruses.
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