For the first time, cameras in Africa captured a 'dynamic network' of wildlife interacting with thousands of infected bats believed to be carrying the Marburg virus, which is a rare but extremely dangerous disease that belongs to the same family as Ebola. The new videos revealed at least 14 different types of animals, including leopards, hyenas, monkeys, birds and rats, actively hunting herds of Egyptian fruit bats.
Ethiopia has confirmed its first outbreak of Marburg virus disease, after nine cases were reported in the south of the country. World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus on Friday commended the Ethiopian Health Ministry and other health agencies for their rapid and transparent response to the outbreak. list of 3 itemsend of list This fast action demonstrates the seriousness of the country's commitment to bringing the outbreak under control quickly, Tedros wrote in a social media post.
Marburg virus (MARV) is a filovirus that causes a severe and often lethal hemorrhagic fever1,2. Despite the increasing frequency of MARV outbreaks, no vaccines or therapeutics are licensed for use in humans. Here, we designed mutations that improve the expression, thermostability, and immunogenicity of the prefusion MARV glycoprotein (GP) ectodomain trimer, which is the sole target of neutralizing antibodies and vaccines in development38.
