Hallucinogen DMT an effective antidepressant in small clinical trial
A single DMT dose produced rapid antidepressant effects, with 44% reporting improvement at one week versus 6% in control; benefits declined by 14 weeks.
Single dose of potent psychedelic drug could help treat depression, trial shows
A single intravenous DMT dose combined with psychotherapy produced rapid, sustained antidepressant effects lasting three to six months in treatment-resistant depression.
Therapists, including experienced clinicians, require ongoing supervision and consultation to navigate boundary complexities and ethical challenges in psychedelic-assisted therapy.
