Bowen: 49ers quarterback Brock Purdy will have defined reads versus the Eagles' split-safety coverages. That's the play-action throws in Shanahan's game plan, plus the concepts designed to lift the safeties and create middle-of-the-field voids. Christian McCaffrey will see volume as a dual-threat option, too, and I like this run game matchup. Best bet: McCaffrey OVER 57.5 rushing yards (-111). McCaffrey has topped the 70-yard rushing mark in five of his past seven games, with 20 or more carries in five of his past six.
First, analytics writer Seth Walder breaks down three stat trends that could be pivotal this weekend. Then, fantasy writer Eric Moody highlights five players who are rostered in less than 50% of ESPN leagues as of Saturday and could be started in a jam. That's followed by NFL analyst Ben Solak's three potential surprises, NFL analyst Matt Bowen's key matchup to watch and sports betting analyst Pamela Maldonado's favorite bet for Week 15.