Testing revealed that quercetin was a potent inhibitor of the enzyme ALDH, which breaks down acetaldehyde, leading to inflammation and headaches linked with alcohol consumption.
The presence of quercetin glucuronide suggests that it disrupts alcohol metabolism, allowing greater amounts of acetaldehyde to circulate and potentially causing adverse effects like headaches.
Secondary effects, such as headaches from quercetin, are difficult to trace because the foods containing quercetin don't typically cause such symptoms, complicating identification of triggers.
Inexpensive red wines might be safer choices for those sensitive to headaches, as they are often made from grapes that receive less sunlight, hence lower quercetin levels.
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