Todd Howard steps in to double down that yes, Fallout: New Vegas is canon to Amazon's Fallout
Briefly

Bethesda's Todd Howard confirmed that Fallout: The Series is canon to Fallout: New Vegas and Fallout 4, taking place in 2296 and impacting game lore significantly.
The idea of the destruction of Shady Sands in the series, suggested by showrunners, provided a story anchor and coherence with the game universe, carefully handled to remain consistent.
The series creators were careful to respect and maintain the consistency of the Fallout universe, ensuring that all events from the previous games, including New Vegas, are acknowledged in the series.
Read at VG247
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