In Diablo 4's expansion, players can unlock powerful Runewords by combining two runes in a suitable item, adding significant depth and strategy to gameplay.
Runewords are essential for maximizing gameplay potential, as they offer unique bonuses when crafted correctly. You can only have two active at once, encouraging thoughtful combinations.
The questline for the Vessel of Hatred introduces players to Runeword mechanics, providing an initial set of Runes and instructions to maximize their usage in battle.
Farming for specific Runes is not currently available, but players can still find Runes from various loot sources, generally at a higher drop rate.
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