"Over the past few years GLP-1 drugs have gone from relatively obscure diabetes medications to household names for weight loss. The trend really took off in 2021, when the FDA approved semaglutide for weight loss, sold under the brand names Ozempic and Wegovy. If you're not taking one, someone in your life likely is. That includes celebrities such as Meghan Trainor and Serena Williams, who say they've used GLP-1 injectables."
"GLP-1 is glucagon-like peptide 1. It is produced in the intestine in response to food intake, so, like, when you eat, it is produced. It usually, actuallyit circulates in the blood, but it is cut off pretty quick. Pierre-Louis: Mm-hmm. Brookshire: You have an enzyme that usually breaks it down very quickly. And what this does is it increases your insulin secretion; it inhibits anothe"
GLP-1 (glucagon-like peptide 1) is produced in the intestine in response to food intake and circulates briefly in the blood before being rapidly broken down by an enzyme. Therapeutic GLP-1 drugs mimic this hormone to increase insulin secretion and inhibit other signals, producing effects useful for diabetes management and weight loss. Semaglutide received FDA approval for weight loss in 2021 and is marketed as Ozempic and Wegovy. GLP-1 injectables have become popular for weight loss, including among celebrities. Drugmakers are developing newer, more potent formulations, including the first oral Wegovy-based pill, and research is exploring additional medical uses.
Read at www.scientificamerican.com
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