"The Chan Zuckerberg Initiative is making big changes, and it started 2026 with some job cuts to recalibrate and refocus its efforts on AI-powered biomedical research. The philanthropic organization, formed by Meta cofounder and CEO Mark Zuckerberg and his wife, Dr. Priscilla Chan, is cutting about 70 jobs, or roughly 8% of its workforce, a CZI spokesperson confirmed to Fortune. The layoffs happened primarily at the organization's Redwood City headquarters in San Mateo, Calif."
"Their move extends a broader retreat from the couple's earlier push into education and social-justice causes, although they'll continue to make donations to local organizations. "I feel like the science work that we've done, the Biohub model in particular, has been the most impactful thing that we have done," Zuckerberg said during an event at the Biohub Imaging Institute in Redwood City in November, according to the Associated Press."
The Chan Zuckerberg Initiative cut about 70 jobs, roughly 8% of its workforce, primarily at its Redwood City headquarters, to recalibrate and refocus on AI-powered biomedical research. Leadership intends to remake the philanthropy around AI-driven science and to expand the Biohub network as the flagship program. The organization is stepping back from earlier priorities such as education, criminal justice reform, housing, and community development while maintaining donations to local groups. The founders have committed, via the Giving Pledge, to give away 99% of lifetime wealth. The shift reflects a broader trend of major donors prioritizing science-focused, tech-centric philanthropy.
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