Research from Northwestern University indicates that the hippocampus undergoes changes that lead to 'representation drift,' where spatial memories do not remain fixed. Mice were studied in a treadmill-based maze setup while their brain activity was monitored with advanced imaging techniques. The findings suggest that even when the environment stays unchanged, the patterns of memory representation evolve. This contradicts earlier hypotheses that environmental factors primarily drive representational changes, highlighting the brain's dynamic memory processing mechanisms.
This study reveals that changes in the brain's hippocampus over time can cause memories related to spatial navigation to shift, rather than remain stable.
Mice navigated a treadmill-based maze while brain activity was monitored, showing that representation drift occurs independently of environmental changes.
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