Safety Talanoa Hufanga's wrist injury will sideline him for at least a month, opening the door for rookie Malik Mustapha to step up.
Coach Kyle Shanahan noted Mustapha's impressive start, especially his ability to engage quickly and make impactful plays, despite some missed tackles.
The 49ers face a growing injury list, with Hufanga and kicker Jake Moody potentially joining injured reserve, testing the team's depth and resilience.
San Francisco's defense struggled with missed tackles in recent games, particularly highlighted in their losses, indicating areas needing improvement against Kenneth Walker III.
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